journal cover

Molecular basis of CTCF binding polarity in genome folding

bioRxiv

Dec 14, 2019

Elphège P. NoraBenoit G. Bruneau

Abstract

Current models propose that boundaries of mammalian topologically associating domains (TADs) arise from the ability of the CTCF protein to stop extrusion of chromatin loops by cohesin proteins ([Merkenschlager & Nora, 2016][1]; [Fudenberg, Abdennur, Imakaev, Goloborodko, & Mirny, 2017][...read more

Mentioned in this Paper

Chromatin
Mutant Proteins
CCCTC-binding factor, human
Mutant
Cohesins
Genome
Cell Polarity
Protein Domain
Site
Single Molecule Imaging
136
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Chaperones & Protein Folding (Preprints)

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here are the latest preprints on chaperone proteins.

Human Cell Atlas Consortium

The aim of the Human Cell Atlas is to build reference maps of all human cells in order to enhance our understanding of health and disease. Follow the latest research from the Human Cell Atlas Consortium here.

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Rotavirus Infections

Rotavirus infections often lead to gastroenteritis. Symptoms include diarrhea, vomiting, fever, and dehydration. Discover the latest research on rotavirus infections here.

Cytoskeleton & Cell Polarity

A dynamic cytoskeleton is critical for the generation of cell polarity. This feed focuses on cell polarity and the cytoskeleton, including actin and microtubular cytoskeletal organization.

BioHub - Researcher Network

The Chan-Zuckerberg Biohub aims to support the fundamental research and develop the technologies that will enable physicians to cure, prevent, or manage all diseases in our childrens' lifetimes. The CZ Biohub brings together researchers from UC Berkeley, Stanford, and UCSF. Find the latest research from the CZ Biohub researcher network here.

Chaperones & Protein Folding

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.

Cytoskeleton & Cell Polarity

A dynamic cytoskeleton is critical for the generation of cell polarity. This feed focuses on cell polarity and the cytoskeleton, including actin and microtubular cytoskeletal organization.

Institut Curie - Centre de Recherche

Institut Curie - Centre de Recherche covers multiple areas of research: the biology of radiations, cell signaling and Cancer, second Development biology, Cancer, Genetics and Epigenetics, third integrative tumor biology, immunology and environment, and fourth multiscale Physics-Biology-Chemistry and Cancer. Follow this feed to stay updated on research from this group.

Related Papers

bioRxiv

Absolute quantification of cohesin, CTCF and their regulators in human cells

bioRxivFebruary 26, 2019
Johann HolzmannJan-Michael Peters
ELife

Absolute quantification of cohesin, CTCF and their regulators in human cells

ELifeJune 18, 2019
Johann HolzmannJan-Michael Peters
© 2020 Meta ULC. All rights reserved

Molecular basis of CTCF binding polarity in genome folding

bioRxiv

Dec 14, 2019

Elphège P. NoraBenoit G. Bruneau

PMID: 990876177

DOI: 10.1101/2019.12.13.876177

Abstract

Current models propose that boundaries of mammalian topologically associating domains (TADs) arise from the ability of the CTCF protein to stop extrusion of chromatin loops by cohesin proteins ([Merkenschlager & Nora, 2016][1]; [Fudenberg, Abdennur, Imakaev, Goloborodko, & Mirny, 2017][...read more

Mentioned in this Paper

Chromatin
Mutant Proteins
CCCTC-binding factor, human
Mutant
Cohesins
Genome
Cell Polarity
Protein Domain
Site
Single Molecule Imaging
136

Similar Papers Found In These Feeds

Chaperones & Protein Folding (Preprints)

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here are the latest preprints on chaperone proteins.

Human Cell Atlas Consortium

The aim of the Human Cell Atlas is to build reference maps of all human cells in order to enhance our understanding of health and disease. Follow the latest research from the Human Cell Atlas Consortium here.

Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/molecular-basis-of-ctcf-binding-polarity-in/990876177