Molecular biology as a tool for the treatment of cancer.

Clinical and Experimental Medicine
Carla de Castro Sant' AnnaRommel Rodriguez Burbano

Abstract

Cancer is a genetic disease characterized by uncontrolled cell growth and metastasis. Cancer can have a number of causes, such the activation of oncogenes, the inactivation of tumor-suppressing genes, mutagenesis provoked by external factors, and epigenetic modifications. The development of diagnostic tools and treatments using a molecular biological approach permits the use of sensitive, low-cost, noninvasive tests for cancer patients. Biomarkers can be used to provide rapid, personalized oncology, in particular the molecular diagnosis of chronic myeloid leukemia, and gastric, colon, and breast cancers. Molecular tests based on DNA methylation can also be used to direct treatments or evaluate the toxic effects of chemotherapy. The adequate diagnosis, prognosis, and prediction of the response of cancer patients to treatment are essential to ensure the most effective therapy, reduce the damaging effects of treatment, and direct the therapy to specific targets, and in this context, molecular biology has become increasingly important in oncology. In this brief review, we will demonstrate the fundamental importance of molecular biology for the treatment of three types of cancer-chronic myeloid leukemia, hereditary diffuse gastric c...Continue Reading

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Citations

Jun 7, 2019·Environmental Science and Pollution Research International·Sandra YamashiroRegina Maura Bueno Franco
Dec 25, 2019·Journal of Neurogenetics·Ari Berkowitz
Sep 29, 2019·Clinical and Experimental Medicine·Nataliya BabyshkinaEvgeny Choynzonov
May 26, 2020·Clinical and Experimental Medicine·Munevver BaranArzu Yay
Jan 11, 2021·Clinical and Experimental Medicine·Shangfa GaoNing Liu
Mar 24, 2021·The Journal of International Medical Research·Enfan ZhangJingsong He
Jun 26, 2021·Technology in Cancer Research & Treatment·Brooke E SandersBenjamin G Bitler

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