Molecular biology in ophthalmology. A review of principles and recent advances

Archives of Ophthalmology
N G Della

Abstract

Molecular biology is a young scientific discipline that has already had a profound impact on biomedical science, including basic and clinical eye research. In the coming years, molecular advances will increasingly influence aspects of diagnosis, prognosis, and therapy in clinical ophthalmology. Our current understanding of ocular pathophysiology and classification of eye disease will be advanced and challenged by new discoveries in molecular biology. A knowledge of genotype can clarify apparent phenotype. At the present time, diagnostic tests in ophthalmology for both acquired and inherited diseases are being revolutionized by molecular technology. The molecular genetics of ocular disease is currently the subject of intense investigation using techniques of gene mapping and isolation. Rapid progress in understanding the molecular basis of eye diseases will advance the treatment of these conditions, including the potential for gene therapy.

Citations

Apr 27, 1999·The British Journal of Ophthalmology·E M ElnifroA B Tullo
Oct 12, 2000·Clinical Microbiology Reviews·E M ElnifroP E Klapper
Feb 18, 1998·Lancet·N Okhravi, S Lightman
Oct 3, 2006·Ophthalmology·Robert SamburskyElisabeth J Cohen
Nov 5, 1997·American Journal of Ophthalmology·K F Damji, R R Allingham
May 1, 1996·Australian and New Zealand Journal of Ophthalmology·N G Della
Feb 13, 2020·Angewandte Chemie·Zheng ZhaoBen Zhong Tang
May 5, 2007·Optometry : Journal of the American Optometric Association·Robert P SamburskyElisabeth J Cohen

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