Molecular Characterization and Bioactivity of Coumarin Derivatives from the Fruits of Cucumis bisexualis

Journal of Agricultural and Food Chemistry
Qinge MaQing Yu

Abstract

Cucumis bisexualis (Cucurbitaceae) is known as "mapao egg" or "muskmelon egg", which has been widely used as a wild melon in Chinese folk. Nine new coumarin derivatives (1-9), named 7-hydroxy-3-(4',6'-dihydroxy-5'-isopropyl-3″,3″-dimethyl-2 H-chromen)-6-prenyl-2 H-chro-men-2-one (1), 7-hydroxy-3-(5'-prenyl-3″,3″-dimethyl-2 H-chromen)-6-prenyl-2 H-chromen-2-one (2), 3-(6'-hydroxy-5'-prenyl-3″,3″-dimethyl-2 H-chromen)-6-prenyl-2 H-chromen-2-one (3), 3-(5'-ethyl-3″,3″-dimethyl-2 H-chromen)-6-prenyl-2 H-chromen-2-one (4), 3-(4',6'-dihydroxy-5'-dimeth-ylallyl-3″,3″-dimethyl-2 H-chromen)-6-prenyl-2 H-chromen-2-one (5), 3-[4',6'-dihydroxy-5'-(2-pro-penyl)-3″,3″-dimethyl-2 H-chromen]-14,15-dimethyl-pyrano-chromen-2-one (6), 3-(6'-dihydroxy-5'-isopropanol-3″,3″-dimethyl-2 H-chromen)-14,15-dimethyl-pyrano-chromen-2-one (7), 3-(5'-iso-pentenol-3″,3″-dimethyl-2 H-chromen)-14,15-dimethyl-pyrano-chromen-2-one (8), 3-(4',6'-dihydr-oxy-5'-prenyl-3″,3″-dimethyl-2 H-chromen)-14,15-dimethyl-pyrano-chromen-2-one (9), together with 12 known compounds (10-21), were isolated and identified by spectroscopic analysis and references from the active site (EtOAc soluble fraction) of the fruits of C. bisexualis for the first time. Compounds (1-21) were eva...Continue Reading

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Citations

May 6, 2020·Journal of Food Biochemistry·Qinge MaZhipei Sang
Jun 23, 2020·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Qin-Ge MaZhi-Pei Sang
Jan 16, 2019·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Rong-Rui WeiZhi-Pei Sang
May 19, 2021·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Rong-Rui Wei, Qin-Ge Ma
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ioanna KostopoulouAnastasia Detsi

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