Molecular characterization of a novel mitovirus from the plant‑pathogenic fungus Botryosphaeria dothidea.

Archives of Virology
Hong LiuQian Zhou

Abstract

Here, a novel mycovirus, Botryosphaeria dothidea mitovirus 1 (BdMV1), was isolated from a phytopathogenic fungus, Botryosphaeria dothidea, and its molecular characteristics were determined. BdMV1 has a genome of 2,667 nt that contains a single large open reading frame (ORF) using the fungal mitochondrial genetic code. The ORF encodes an RNA-dependent RNA polymerase (RdRp) of 727 amino acids with a molecular mass of 81.64 kDa. BLASTp analysis revealed that the RdRp domain of BdMV1 has 39.59% and 39.18% sequence identity to Plasmopara viticola associated mitovirus 43 and Setosphaeria turcica mitovirus 1, respectively. Phylogenetic analysis further suggested that BdMV1 is a new member of the genus Mitovirus within the family Mitoviridae. To the best of our knowledge, this is the first report of a mitovirus in B. dothidea.

References

Sep 12, 2007·Bioinformatics·M A LarkinD G Higgins
Jan 24, 2009·Molecular Plant Pathology·Michael N PearsonKieren Arthur
Apr 30, 2009·Annual Review of Phytopathology·Said A Ghabrial, Nobuhiro Suzuki
Apr 21, 2010·Proceedings of the National Academy of Sciences of the United States of America·Xiao YuXianhong Yi
Mar 19, 2013·Advances in Virus Research·Bradley I Hillman, Guohong Cai
Mar 17, 2015·Virology·Said A GhabrialNobuhiro Suzuki
Mar 24, 2016·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura
May 6, 2017·Archives of Virology·Yi ChenJie Zhong
Oct 19, 2017·Nucleic Acids Research·Elliot J LefkowitzDonald B Smith
Jul 26, 2018·PloS One·Jan ZollWillem J G Melchers

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Datasets Mentioned

BETA
ALD89116.1
AHY03257.1

Software Mentioned

ClustalX
BLASTp
MEGA
GeneDoc

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