journal cover

Molecular Characterization of A(1) and A(2a) Adenosine Receptors

Drug Development Research

Mar 1, 1993

K A JacobsonG L Stiles

Abstract

Detailed amino acid sequence analyses of A(1) and A(2a) adenosine receptors were assembled by analogy to other G-protein-coupled receptors and correlated with pharmacological observations. Sites for phosphorylation, palmitoylation, and sodium binding have been proposed. Striatal A(2a) r...read more

Mentioned in this Paper

Receptors, Purinergic P1
Tissue Membrane
2-(4-(2-(2-((4-aminophenyl)methylcarbonylamino)ethylaminocarbonyl)ethyl)phenyl)ethylamino-5'-N-ethylcarboxamidoadenosine
Adenosine
Phenyl
G-Protein-Coupled Receptors
CGS 21680
Isothiocyanates
Protein Phosphorylation
Bos taurus
Paper Details
References
  • References6
  • Citations7
1
  • References6
  • Citations7
1

Similar Papers Found In These Feeds

GPCRs Signaling Pathway

G-protein coupled receptors (GPCRs) are membrane receptors implicated in the pathophysiology of various diseases, including neurodegenerative disorders, infectious diseases, and cancer. Here is the latest research on GPCR signaling pathway.

G-Protein-Coupled Receptors

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.

Phosphoproteomics

Phosphoproteomics refers to the identification and quantification of phosphorylated proteins in the proteome. This approach provides a high-throughput method of examining the state of intracellular phosphorylation. Here is the latest research on phosphoproteomics.

Related Papers

© 2020 Meta ULC. All rights reserved

Molecular Characterization of A(1) and A(2a) Adenosine Receptors

Drug Development Research

Mar 1, 1993

K A JacobsonG L Stiles

PMID: 23002320

DOI: 10.1002/ddr.430280307

Abstract

Detailed amino acid sequence analyses of A(1) and A(2a) adenosine receptors were assembled by analogy to other G-protein-coupled receptors and correlated with pharmacological observations. Sites for phosphorylation, palmitoylation, and sodium binding have been proposed. Striatal A(2a) r...read more

Mentioned in this Paper

Receptors, Purinergic P1
Tissue Membrane
2-(4-(2-(2-((4-aminophenyl)methylcarbonylamino)ethylaminocarbonyl)ethyl)phenyl)ethylamino-5'-N-ethylcarboxamidoadenosine
Adenosine
Phenyl
G-Protein-Coupled Receptors
CGS 21680
Isothiocyanates
Protein Phosphorylation
Bos taurus

Similar Papers Found In These Feeds

GPCRs Signaling Pathway

G-protein coupled receptors (GPCRs) are membrane receptors implicated in the pathophysiology of various diseases, including neurodegenerative disorders, infectious diseases, and cancer. Here is the latest research on GPCR signaling pathway.

G-Protein-Coupled Receptors

G-protein-coupled receptors (GPCRs), the largest family of integral membrane proteins, participate in the regulation of many physiological functions and are the targets of approximately 30% of currently marketed drugs. Here is the latest research.

Related Papers

European Journal of Pharmacology

Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor

European Journal of PharmacologyJune 15, 1994
A P IJzermanK A Jacobson
Paper Details
References
  • References6
  • Citations7
1
  • References6
  • Citations7
1
/papers/molecular-characterization-of-a1-and-a2a/23002320