Molecular characterization of epidemic ciprofloxacin- and methicillin-resistant Staphylococcus aureus strains colonizing patients in an intensive care unit.

Journal of Clinical Microbiology
E E UdoT D Chugh

Abstract

Eighteen methicillin-resistant Staphylococcus aureus (MRSA) samples isolated from patients and the environment in an intensive care unit (ICU) during a routine surveillance were tested for antimicrobial resistance and typed by pulsed-field gel electrophoresis. Three pulsed-field patterns were observed. Sixteen were ciprofloxacin resistant and had identical pulsed-field patterns. The results suggested that a ciprofloxacin-resistant MRSA clone had contaminated the environment and spread among patients. This study demonstrates the application of infection control surveillance combined with strain typing in detecting MRSA colonization in the ICU where it was not known to exist.

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Citations

Feb 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D C Hooper
Dec 7, 2007·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·E E UdoA Al-Asar
Dec 13, 2005·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·E E UdoP W J West
Apr 9, 2001·Critical Care Medicine·D K Warren, V J Fraser
Apr 2, 1999·Antimicrobial Agents and Chemotherapy·J E GustafsonW B Grubb
Sep 11, 2002·The Lancet Infectious Diseases·David C Hooper

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