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Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis

Frontiers in Immunology

Aug 20, 2019

Emmanuel KarouzakisLisa G M van Baarsen

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Abstract

Rheumatoid arthritis (RA) is a progressive, destructive autoimmune arthritis. Break of tolerance and formation of autoantibodies occur years before arthritis. Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) play a crucial role in shaping the immu...read more

Mentioned in this Paper

Antigens
Arthritis
Rheumatoid Arthritis
Autoantibodies
Malignant Neoplasms
Cell Cycle
Collagen
Cytoskeleton
DNA
Extracellular Matrix
6
1
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Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis

Frontiers in Immunology

Aug 20, 2019

Emmanuel KarouzakisLisa G M van Baarsen

PMID: 31481955

DOI: 10.3389/fimmu.2019.01863

Abstract

Rheumatoid arthritis (RA) is a progressive, destructive autoimmune arthritis. Break of tolerance and formation of autoantibodies occur years before arthritis. Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) play a crucial role in shaping the immu...read more

Mentioned in this Paper

Antigens
Arthritis
Rheumatoid Arthritis
Autoantibodies
Malignant Neoplasms
6
1

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