Molecular characterization of rabies viruses from two western provinces of the Democratic Republic of the Congo (2008-2017).

Virus Genes
Georges Tshilenge MbuyiWilliam G Dundon

Abstract

Although rabies is enzootic in the Democratic Republic of the Congo, there is very little molecular epidemiological information about the viruses circulating in animals. In this study, a fragment of the rabies virus (RABV) nucleoprotein gene was amplified and sequenced from 21 animal brain samples collected in two western provinces of the country between 2008 and 2017. The samples tested were from cat (n = 1), dog (n = 17), goat (n = 2), and sheep (n = 1). Phylogenetic analysis revealed that the sequences generated were highly similar to each other and belonged to lineage Africa 1b clustering with a single sample identified in a canine in the Republic of Congo in 2014. This is the first molecular epidemiological study of RABV in the DRC and the data generated will assist authorities in the development of effective control strategies for rabies in the country.

References

May 31, 2002·The Veterinary Record·Y H Ali
Dec 9, 2009·Zoonoses and Public Health·P De BenedictisI Capua
Mar 11, 2011·Journal of Clinical Microbiology·Paola De BenedictisGiovanni Cattoli
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Nov 25, 2014·Pathogens and Global Health·Delphin I MuyilaMathilde B Ekila
Feb 10, 2017·Tropical Animal Health and Production·Ibrahim AhmadIshaya S Tekki
Dec 1, 2017·Nature Reviews. Disease Primers·Anthony R FooksAshley C Banyard
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Apr 2, 2020·Viruses·Claude T SabetaAnthony R Fooks
May 15, 2020·Acta Tropica·Céline MbiloJakob Zinsstag

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Datasets Mentioned

BETA
MN264710
MN264691
MN264711

Methods Mentioned

BETA
PCR

Software Mentioned

MEGA6

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