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Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily

Proceedings of the National Academy of Sciences of the United States of America

Jun 15, 1992

I VigonM Souyri

PMID: 1608974

Abstract

We have cloned the human homolog of the v-mpl oncogene transduced in the myeloproliferative leukemia retrovirus, which presents striking homologies with members of the hematopoietin receptor superfamily. We obtained two types of clones, MPLP and MPLK, which had the same 5' extremity but...read more

Mentioned in this Paper

Genes, Reiterated
Transcription, Genetic
Thrombopoietin Receptor
DNA, Neoplasm
Protein Conformation
Receptors, Colony-Stimulating Factor
Homologous Sequences, Nucleic Acid
MPLK protein, human
Retroviridae Proteins, Oncogenic
Poly(A) Tail
39
1
Paper Details
References
  • References26
  • Citations237
123
  • References26
  • Citations237
12345...

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Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily

Proceedings of the National Academy of Sciences of the United States of America

Jun 15, 1992

I VigonM Souyri

PMID: 1608974

DOI:

Abstract

We have cloned the human homolog of the v-mpl oncogene transduced in the myeloproliferative leukemia retrovirus, which presents striking homologies with members of the hematopoietin receptor superfamily. We obtained two types of clones, MPLP and MPLK, which had the same 5' extremity but...read more

Mentioned in this Paper

Genes, Reiterated
Transcription, Genetic
Thrombopoietin Receptor
DNA, Neoplasm
Protein Conformation
Receptors, Colony-Stimulating Factor
Homologous Sequences, Nucleic Acid
MPLK protein, human
Retroviridae Proteins, Oncogenic
Poly(A) Tail
39
1

Feeds With Similar Papers

Myelodysplastic Syndromes

Myelodysplastic syndromes are cancers in which immature blood cells in the bone marrow do not mature to become healthy blood cells. Discover the latest research on this cancer here.

Paper Details
References
  • References26
  • Citations237
123
  • References26
  • Citations237
12345...

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