PMID: 6159625Jul 1, 1980Paper

Molecular cloning of human interferon cDNA

Proceedings of the National Academy of Sciences of the United States of America
T TaniguchiM Muramatsu

Abstract

A hybrid plasmid, TpIF319, has been shown to contain the sequence for human fibroblast interferon mRNA [Taniguchi, T., Sakai, M., Fujii-Kuriyama, Y., Muramatsu, M., Kobayashi, S. & Sudo, T. (1979) Proc. Jpn. Acad. 55, Ser. B, 464-469]. This conclusion was confirmed by a hybridization-translation assay, using rabbit globin mRNA and its cDNA-containing plasmid as a control. Plasmid TpIF319 was used as probe and another recombinant plasmid, TpIF319-13, whose cDNA insert consists of about 800 base pairs, was isolated. Nucleotide sequence analysis of the cDNA revealed that the DNA in fact codes for human fibroblast interferon.

References

Jun 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·E A HavellJ Vilcek
Mar 4, 1977·Annals of the New York Academy of Sciences·J VilcekS Yamazaki
May 11, 1978·Nature·W FiersM Ysebaert
Feb 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·A M Maxam, W Gilbert
Aug 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R L CavalieriS Pestka
Feb 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M RubinsteinS Pestka
Feb 11, 1976·Proceedings of the National Academy of Sciences of the United States of America·E Knight
Oct 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M Grunstein, D S Hogness
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·C L PrivesE Winocour
Nov 1, 1974·Japanese Journal of Microbiology·J SuzukiS Kobayashi
Jun 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·H Aviv, P Leder
Jul 1, 1974·European Journal of Biochemistry·W M Bonner, R A Laskey
Jun 1, 1980·Gene·T TaniguchiM Muramatsu
Sep 12, 1957·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A ISAACS, J LINDENMANN

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Citations

Jan 1, 1982·Archives of Virology·F H Sarkar, S L Gupta
Aug 19, 1993·Biochimica Et Biophysica Acta·T TamaiH Murakami
Jun 1, 1980·Gene·T TaniguchiM Muramatsu
Jun 9, 2005·Fish & Shellfish Immunology·Børre Robertsen
Apr 6, 2004·Trends in Pharmacological Sciences·Jan Vilcek, Marc Feldmann
Sep 18, 2010·Nature Reviews. Immunology·Thirumala-Devi Kanneganti
Sep 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·T TaniguchiM Ptashne
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·S Ohno, T Taniguchi
Jan 1, 1984·Biotechnology & Genetic Engineering Reviews·M D Edge, R Camble
Sep 1, 1982·The Journal of Experimental Medicine·A D SagarF H Ruddle
Oct 1, 1987·Journal of Interferon Research·T Taniguchi
Jul 11, 1985·Nucleic Acids Research·R Hauptmann, P Swetly
Nov 15, 2008·Annual Review of Immunology·Marc Feldmann
Nov 5, 2008·The Journal of Clinical Investigation·Marc Feldmann
Dec 9, 2008·Immunology Letters·Cláudio A BonjardimErna G Kroon
Jun 5, 2007·Biochimie·Mounira K Chelbi-Alix, Juana Wietzerbin
Jan 6, 2009·Immunological Reviews·Mitsutoshi Yoneyama, Takashi Fujita
Aug 21, 2013·Immunological Reviews·Russell K DurbinJoan E Durbin
Jun 1, 1982·The Journal of Pediatrics·S E AntonarakisH H Kazazian
Nov 10, 2016·Viruses·Pierre BoudinotJean-Pierre Levraud
Aug 1, 1986·Immunological Reviews·T TaniguchiG Yamada
Apr 1, 1986·European Journal of Biochemistry·Y AmayaM Mori
Jan 15, 1986·European Journal of Biochemistry·S MiuraM Mori
Oct 9, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ahmad A TarhiniJohn M Kirkwood
May 1, 1982·Molecular and Cellular Biology·P M PithaF H Ruddle

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