PMID: 9524220Apr 3, 1998Paper

Molecular cloning of the cDNA encoding A + U-rich element RNA binding factor

Biochimica Et Biophysica Acta
A DoiS Fujita

Abstract

Using the differential display method, a new cDNA clone, termed laAUF1, encoding the human A + U-rich RNA-binding motif was isolated and sequenced. Analysis of the protein sequence of laAUF1 indicates 73% homology between the deduced polypeptide sequences of laAUF1 and AUF1 in the region encoding a consensus motif for two non-identical RNA recognition motifs (RRMs) and Gln-rich motif. We suggest that the similar affinities of laAUF1 and AUF1 for particular A + U-rich elements (ARE) sequences are related to their potencies as mRNA destabilizers.

References

Feb 21, 1992·Cell·C A KeleherA D Johnson
Jan 1, 1990·Annual Review of Genetics·J A AtwaterI M Verma
Jan 1, 1985·Pharmacology & Therapeutics·P B Fisher, S Grant
Apr 1, 1989·Genes & Development·R J BandziulisG Dreyfuss
Jun 21, 1994·Proceedings of the National Academy of Sciences of the United States of America·L P AielloG L King

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Citations

Sep 9, 2016·American Journal of Medical Genetics. Part a·Xuyun HuYiping Shen
Dec 29, 2011·The Journal of Biological Chemistry·Vishram P KedarPerry J Blackshear
Dec 22, 2017·RNA·Katrin KemmererJulia E Weigand

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