PMID: 9557959Apr 29, 1998Paper

Molecular cloning of the cDNA encoding the constant region of the immunoglobulin A heavy chain (C alpha) from a marsupial: Trichosurus vulpecula (common brushtail possum)

Immunology Letters
Katherine BelovD W Cooper

Abstract

A cDNA encoding the brushtail possum immunoglobulin A heavy chain constant region (C alpha) was isolated by screening a mesenteric lymph node cDNA library with a porcine C alpha exon 3 probe. The larger of the two positive clones isolated (Tv4a) consisted of 1325 bp of possum cDNA that included an open reading frame of 1191 bp. Its deduced amino acid sequence had a high degree of sequence identity with known eutherian C alpha sequences. This clone appears to encode the entire possum IgA heavy chain constant region. The possum C alpha sequence had a nucleotide sequence identity of 57.7% with porcine C alpha, 51% with mouse C alpha, 46.7% with dog C alpha and 45.9% with human C alpha2. The corresponding amino acid identities were 46.7, 45.6, 49.4 and 49%, respectively.

References

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Citations

Oct 15, 1998·Molecular Reproduction and Development·K E Mate, C A McCartney
Apr 28, 2000·Developmental and Comparative Immunology·J M Old, E M Deane
Apr 28, 2000·Developmental and Comparative Immunology·R D Miller, K Belov
Oct 16, 2002·Developmental and Comparative Immunology·Katherine BelovDesmond W Cooper
Apr 9, 2001·Veterinary Immunology and Immunopathology·K BelovD W Cooper
Jun 29, 2002·Veterinary Immunology and Immunopathology·Renée R RawsonDesmond W Cooper
Dec 12, 2003·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Katherine Belov, Lars Hellman
Mar 29, 2002·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·K BelovD W Cooper
Apr 13, 2000·Immunology and Cell Biology·P D ZuccolottoE M Deane
Sep 24, 2004·Immunology·Jenny M Woof, Michael A Kerr
Mar 17, 2004·Reproduction, Fertility, and Development·D J Kay, A L Kitchener
Apr 22, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Michelle L BakerRobert D Miller

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