Molecular complexity determines the number of olfactory notes and the pleasantness of smells.

Scientific Reports
F KermenMoustafa Bensafi

Abstract

One major unresolved problem in olfaction research is to relate the percept to the molecular structure of stimuli. The present study examined this issue and showed for the first time a quantitative structure-odor relationship in which the more structurally complex a monomolecular odorant, the more numerous the olfactory notes it evokes. Low-complexity odorants were also rated as more aversive, reflecting the fact that low molecular complexity may serve as a warning cue for the olfactory system. Taken together, these findings suggest that molecular complexity provides a framework to explain the subjective experience of smells.

References

Sep 27, 1974·Annals of the New York Academy of Sciences·S S Schiffman
Jul 1, 1970·The Journal of General Physiology·M M Mozell
Aug 1, 1997·Perceptual and Motor Skills·S Ayabe-KanamuraS Saito
Mar 25, 1999·Cell·B MalnicL B Buck
Jun 21, 2001·Journal of Chemical Information and Computer Sciences·M M HannG Harper
Feb 7, 2003·Journal of the American College of Cardiology·Javier BermejoMiguel A García-Fernández
Aug 30, 2003·Neuroscience and Biobehavioral Reviews·Donald A Wilson, Richard J Stevenson
May 1, 1954·Nature·R H WRIGHT
Jul 30, 1964·Annals of the New York Academy of Sciences·J E AMOORE
Dec 4, 2003·Journal of Experimental Psychology. General·Rachel S Herz
Sep 15, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rehan M KhanNoam Sobel
Sep 18, 2007·Nature·Andreas KellerHiroaki Matsunami
Jan 17, 2009·PloS One·Nathalie MandaironAnne Didier
Mar 6, 2009·Science Signaling·Harumi SaitoJoel D Mainland
Aug 19, 2009·Annals of the New York Academy of Sciences·Catherine RoubyMoustafa Bensafi
Dec 29, 2009·Behavioural Brain Research·Johan PonceletThomas Hummel
Jul 9, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rafi HaddadNoam Sobel
Oct 20, 2010·Chemical Senses·Fanny RinckMoustafa Bensafi
Nov 17, 2010·PloS One·Johan PonceletMoustafa Bensafi

❮ Previous
Next ❯

Citations

Nov 22, 2012·Proceedings of the National Academy of Sciences of the United States of America·Tali WeissNoam Sobel
May 3, 2013·PloS One·Pauline JoussainMoustafa Bensafi
Feb 10, 2016·Journal of Chemical Information and Modeling·Thomas Böttcher
Mar 19, 2016·Human Brain Mapping·A FournelM Bensafi
May 11, 2013·Journal of Neuroscience Methods·C SezilleM Bensafi
Jan 21, 2014·Current Opinion in Neurobiology·Lavi SecundoNoam Sobel
Feb 28, 2015·Food Chemistry·Arielle J JohnsonSusan E Ebeler
Jun 29, 2013·Neuroscience and Biobehavioral Reviews·Benjamin Auffarth
Jun 12, 2014·Frontiers in Psychology·Thierry Thomas-DanguinGérard Coureaud
Aug 31, 2016·Drug Discovery Today·Oscar Méndez-Lucio, José L Medina-Franco
Dec 9, 2016·Scientific Reports·Hamidreza Namazi, Vladimir V Kulish
Jul 17, 2018·Chemical Senses·Charles Spence, Qian Janice Wang
Sep 29, 2018·Foods·Charles Spence
Apr 26, 2019·PLoS Computational Biology·Carmen C LiconMoustafa Bensafi
Jun 20, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Asifa MajidBill S Hansson
Feb 18, 2020·Chemical Senses·Cédric ManesseCamille Ferdenzi
Mar 20, 2020·Chemical Senses·Yue MaYan Xu
Aug 10, 2016·BMC Neuroscience·Andreas Keller, Leslie B Vosshall
Jan 14, 2020·Neuroscience and Biobehavioral Reviews·Benjamin D YoungDennis Mathew
Dec 31, 2019·Computer Methods and Programs in Biomedicine·Shafiul OmamHamidreza Namazi
Oct 24, 2020·Scientific Reports·David T LiuBertold Renner
Jan 16, 2021·Journal of Chemical Information and Modeling·Anju SharmaPritish Kumar Varadwaj
Oct 2, 2021·Brain Structure & Function·Matthias CaveliusAnne Didier

❮ Previous
Next ❯

Software Mentioned

Arctander atlas
Arctander

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.