Molecular control of animal cell cytokinesis.

Nature Cell Biology
Juan Pablo Fededa, Daniel W Gerlich

Abstract

Cytokinesis is the process by which mitotic cells physically split in two following chromosome segregation. Dividing animal cells first ingress a cytokinetic furrow and then separate the plasma membrane by abscission. The general cytological events and several conserved molecular factors involved in cytokinesis have been known for many years. However, recent progress in microscopy, chemical genetics, biochemical reconstitution and biophysical methodology has tremendously increased our understanding of the underlying molecular mechanisms. We discuss how recent insights have led to refined models of the distinct steps of animal cell cytokinesis, including anaphase spindle reorganization, division plane specification, actomyosin ring assembly and contraction, and abscission. We highlight how molecular signalling pathways coordinate the individual events to ensure faithful partitioning of the genome to emerging daughter cells.

References

Nov 1, 1993·The Journal of Cell Biology·D J Fishkind, Y L Wang
Sep 10, 1998·The Journal of Cell Biology·E BiJ R Pringle
Oct 21, 1998·Current Biology : CB·J PowersW Saxton
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·C B Shuster, D R Burgess
Dec 17, 2002·Journal of Cell Science·Michael V DanilchikKimberly Ray
Jun 6, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Karsten Kruse, Frank Jülicher
Aug 9, 2003·Nature·Julie C CanmanE D Salmon
Aug 27, 2003·The Journal of Cell Biology·Rüdiger NeefFrancis A Barr
Jan 28, 2004·The Journal of Biological Chemistry·Reiko BanHirofumi Tanaka
Jul 30, 2004·Nature·Masanori MishimaMichael Glotzer
Sep 24, 2004·Current Biology : CB·Arnaud EchardPatrick H O'Farrell
Sep 24, 2004·Current Biology : CB·Mohan K BalasubramanianMichael Glotzer
Apr 28, 2005·Current Biology : CB·Kausalya Murthy, Patricia Wadsworth
Apr 28, 2005·Current Biology : CB·Annika GuseMichael Glotzer
May 4, 2005·Trends in Cell Biology·Gerd Jürgens
Jun 2, 2005·Proceedings of the National Academy of Sciences of the United States of America·Rafael R Daga, Fred Chang
Jun 7, 2005·Trends in Cell Biology·Fumio Matsumura
Jul 7, 2005·The Journal of Cell Biology·William M BementGeorge von Dassow
Jul 13, 2005·Trends in Cell Biology·Marisa S OteguiAhna R Skop
Aug 5, 2005·Nature·Henrik Bringmann, Anthony A Hyman
Aug 17, 2005·The Journal of Cell Biology·Ozlem YüceMichael Glotzer
Sep 16, 2005·The Journal of Biological Chemistry·Kazuo EmotoMasato Umeda
Oct 4, 2005·Physical Review Letters·D BironE Moses
Dec 13, 2005·Trends in Cell Biology·Jonathon Pines
Dec 15, 2005·Journal of Cell Science·Yukako Nishimura, Shigenobu Yonemura
Feb 8, 2006·Current Biology : CB·Rüdiger NeefFrancis A Barr
Apr 4, 2006·Developmental Biology·Frantisek BaluskaPeter W Barlow
Apr 4, 2006·Developmental Cell·Fumio MotegiAsako Sugimoto
Apr 11, 2006·Proceedings of the National Academy of Sciences of the United States of America·Changjun ZhuWei Jiang
Sep 5, 2006·Current Biology : CB·Ilektra KourantiArnaud Echard

❮ Previous
Next ❯

Citations

Mar 26, 2013·Trends in Cell Biology·John A SchielRytis Prekeris
May 28, 2013·Trends in Cell Biology·Monica Agromayor, Juan Martin-Serrano
Oct 4, 2012·Nature Cell Biology·Arnaud Echard
Jul 23, 2013·Nature Cell Biology·Zuzana HolubcováMelina Schuh
May 16, 2013·Nature Communications·Ming-Ming LiYun-Gui Yang
Nov 24, 2012·Nature Reviews. Molecular Cell Biology·Mar CarmenaWilliam C Earnshaw
Jan 11, 2013·Proceedings of the National Academy of Sciences of the United States of America·Mariya MollovaBernhard Kühn
Jul 24, 2013·The Journal of Cell Biology·Masayuki OnishiJohn R Pringle
Nov 13, 2013·The Journal of Cell Biology·Rebecca A GreenKaren Oegema
Jul 24, 2013·The Journal of Cell Biology·Mohan K Balasubramanian, Evelyn Yaqiong Tao
Jul 26, 2013·Molecular Biology of the Cell·Matthew K MartzPhilip B Wedegaertner
Aug 15, 2013·Molecular Biology of the Cell·Magdalena Bezanilla
Oct 11, 2013·Molecular Biology of the Cell·Hélia NetoGwyn W Gould
Jun 8, 2013·Blood·Elizabeth Traxler, Mitchell J Weiss
Sep 13, 2013·BMC Veterinary Research·Tina RichJanet C Patterson-Kane
Sep 20, 2012·Journal of Cell Science·Kian-Yong LeeMasanori Mishima
Aug 31, 2013·PloS One·Elizabeth J Lawrence, Craig A Mandato
Sep 26, 2013·PloS One·Shinnosuke SuzukiNaojiro Minami
Mar 13, 2014·The Journal of Cell Biology·Rania S RizkMohan L Gupta
Mar 27, 2013·Annual Review of Biochemistry·John McCulloughWesley I Sundquist
May 13, 2014·Nature Cell Biology·Sigrid B ThoresenHarald Stenmark
Aug 12, 2014·Journal of Molecular Biology·Veronica R MoormanA Joshua Wand
Oct 29, 2014·The Journal of Cell Biology·Katerina Ragkousi, Matthew C Gibson
Sep 13, 2015·Critical Reviews in Biochemistry and Molecular Biology·Kazuhisa Nakayama
Apr 23, 2013·Plant Science : an International Journal of Experimental Plant Biology·Ulrich Kutschera, Karl J Niklas
Nov 21, 2015·Cell Cycle·Christelle Benaud, Claude Prigent
Mar 2, 2013·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Elizabeth Faris CrowellArnaud Echard
Mar 2, 2016·The Journal of Cell Biology·Liliane ChristHarald Stenmark
Jan 2, 2016·Seminars in Cell & Developmental Biology·Gwyn W Gould
Mar 6, 2016·Proceedings of the National Academy of Sciences of the United States of America·David J Sherratt
Dec 10, 2014·Developmental Cell·Beata Mierzwa, Daniel W Gerlich
Dec 15, 2015·Nature·Emmanuel DeriveryMarcos Gonzalez-Gaitan
Apr 30, 2013·Developmental Cell·Oscar M LancasterBuzz Baum
Aug 12, 2015·Scientific Reports·Einat PanetAmit Tzur
Sep 27, 2012·Cytoskeleton·Arnaud Echard
Aug 14, 2012·Cytoskeleton·Clemens Cabernard
Oct 3, 2012·Cytoskeleton·Mohan K BalasubramanianKian-Hong Ng
Jul 12, 2013·Journal of Microscopy·L EvansC Bakal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Seminars in Cell & Developmental Biology
Julien Guizetti, Daniel W Gerlich
Trends in Cell Biology
Patrick Steigemann, Daniel W Gerlich
© 2021 Meta ULC. All rights reserved