Molecular dynamic theories in chromatography

Journal of Chromatography. a
Attila Felinger

Abstract

The molecular dynamic model of chromatography is a microscopic model that consists of two fundamental processes: (i) the random migration of the molecules in the mobile phase, and (ii) the random adsorption-desorption of molecules on the stationary phase. The diffusion and drift of the molecules in the mobile phase is usually described with a simple one-dimensional random walk. The adsorption-desorption process is modeled most of the time by a Poisson process that assumes exponential sojourn times of the molecules in both the mobile and the stationary phases. The molecular dynamic model of chromatography can simply be used to characterize the chromatographic process on heterogeneous stationary phases. It has been applied to reversed phase, chiral, size-exclusion, and ion-exchange separations.

References

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Jul 27, 2002·Journal of Chromatography. a·Peter E Krouskop, Victoria L McGuffin
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Citations

Mar 20, 2010·Analytical and Bioanalytical Chemistry·Ibolya KissAttila Felinger
Apr 8, 2014·Analytical Chemistry·Dzmitry HlushkouUlrich Tallarek
Sep 30, 2014·Journal of Chromatography. a·Annamária SepseyAttila Felinger
Sep 25, 2015·Chemical Reviews·Jun Shen, Yoshio Okamoto
Nov 15, 2014·Analytical Chemistry·Lydia Kisley, Christy F Landes
Jan 8, 2010·Journal of Chromatography. a·Torgny Fornstedt
Jan 13, 2009·Journal of Chromatography. a·Yinliang Chen, Yuanming Tang
Dec 17, 2008·Journal of Chromatography. a·Ivett Bacskay, Attila Felinger
Sep 5, 2014·Analytical Chemistry·Joshua N MabryDaniel K Schwartz
Apr 25, 2015·Analytical Chemistry·Gert DesmetKen Broeckhoven
Jul 28, 2015·Journal of Chromatography. a·Nándor Lambert, Attila Felinger
Feb 4, 2014·Journal of Chromatography. a·Annamária SepseyAttila Felinger
Mar 1, 2018·Annual Review of Physical Chemistry·Nicholas A MoringoChristy F Landes
Dec 11, 2020·Journal of Chromatography. a·Yana A Klimova, Leonid D Asnin

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