PMID: 2523972Apr 1, 1989

Molecular genetics in the National Health Service in Britain

Journal of Medical Genetics
R HarrisA P Read

Abstract

A recent report from the Departments of Health draws attention to the value of DNA diagnosis for inherited diseases and the need for planning these services in the National Health Service. There is great potential for preventive medicine, but a major immediate benefit is the newfound ability to exclude the carrier state in many people at risk and to protect fetuses from abortion when, as in most cases, they are shown to be normal by DNA tests. However, the widespread application of these new techniques requires prior evaluation and general acceptance. This will only be obtained after public debate, education of professionals and the population, and the establishment of adequate non-directive genetic counselling services. Some of the points to be considered in setting up molecular genetics laboratories are described.

References

Dec 24, 1997·Molecular Biotechnology·R Elles
Dec 1, 1989·Journal of Medical Genetics·S Bundey, E Boughton
Apr 1, 1989·Journal of Medical Genetics·P S Harper
Jan 1, 1992·Journal of Medical Genetics·H V Firth, R H Lindenbaum
Nov 14, 1997·Journal of Medical Genetics·I R WalpoleC Bower
Feb 27, 2010·Studies in History and Philosophy of Biological and Biomedical Sciences·William Leeming
Mar 31, 1990·BMJ : British Medical Journal·J W Chisholm
Oct 1, 1992·Clinical Genetics·R J RonaS Mandalia

Citations

Jan 1, 1989·Journal of Medical Genetics·P J SinnottT Strachan
Mar 1, 1989·Human Genetics·S Liechti-GallatiH Moser
Nov 28, 1987·Lancet·T StrachanR Harris
Jul 26, 1986·British Medical Journal·D I Craufurd, R Harris
Oct 1, 1988·BMJ : British Medical Journal·A L MeredithP S Harper
Nov 4, 1985·Nature·B J WainwrightR Williamson
Feb 1, 1988·Trends in Genetics : TIG·R Harris
Sep 26, 1987·British Medical Journal·J Scott
Nov 4, 1985·Nature·R WhiteG Vande Woude
Nov 17, 1983·Nature·J F GusellaA Y Sakaguchi

Related Concepts

Polycystic Kidney - Body Part
Genetic Screening Method
Brain Diseases, Metabolic, Inborn
National Health Service, British
Logistics
Pulmonary Cystic Fibrosis
Muscular Dystrophy
Future
Fetus
Preventive Medicine Specialty

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.