Molecular genetics of dopa decarboxylase and biogenic amines in Drosophila

Developmental Genetics
J Hirsh

Abstract

The gene Ddc encodes two isoforms of the enzyme dopa decarboxylase in Drosophila. These gene products catalyze the final steps in the synthesis of the biogenic amines serotonin and dopamine. This article summarizes recent progress in understanding the tissue- and cell-specific regulation of Ddc, which occurs at both the transcription and alternate splicing levels. In addition, results that are pertinent to understanding the roles of biogenic amines in the neurophysiology of Drosophila are discussed.

References

Jan 1, 1985·Molecular & General Genetics : MGG·J L MarshP M Timmons
Apr 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·C E Rozek, N Davidson
Dec 1, 1986·Molecular and Cellular Biology·J HirshS B Scholnick
Jul 1, 1987·Developmental Biology·K D Konrad, J L Marsh
Jun 1, 1981·Molecular and Cellular Biology·J Hirsh, N Davidson
May 5, 1983·Nature·M S Livingstone, B L Tempel
Jun 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·B L TempelW G Quinn

❮ Previous
Next ❯

Citations

Mar 17, 2010·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Divya SitaramanTroy Zars
Mar 1, 1993·Brain Research. Molecular Brain Research·A Le Van ThaiM J Weber
Apr 4, 2000·Insect Biochemistry and Molecular Biology·H K LehmanJ G Hildebrand
Jul 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·D WangF J Ayala
Jul 30, 2010·Proceedings. Biological Sciences·Christopher J ReaumeFrederic Mery
Apr 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Divya SitaramanTroy Zars
Sep 3, 2008·Journal of Insect Physiology·Claude Wicker-Thomas, Mickael Hamann
Jan 26, 2002·Microscopy Research and Technique·Thomas Roeder
May 1, 1994·The Journal of Experimental Zoology·E McCrady, D J Tolin
Mar 19, 2003·Development·Randall S HewesPaul H Taghert

❮ Previous
Next ❯

Related Concepts

Related Feeds

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.