Molecular heterogeneity of Vicia villosa-recognized perineuronal nets surrounding pyramidal and nonpyramidal neurons in the guinea pig cerebral cortex

Brain Research
H OjimaJ Ohyama

Abstract

Of three monoclonal antibodies (mAbs Cat 301, 1B5 and 473) which recognize epitopes on perineuronal nets (PnNs), only mAb 473 displayed considerably varied degrees of staining intensity on Vicia villosa-labeled pyramidal (P) neurons (5%, intensely; 54%, very weakly; and 41%, unstained). These results indicate the heterogeneity on molecular structure or composition of the terminal N-acetylgalactosamine-containing PnNs within P class as well as between P and nonpyramidal classes.

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Citations

Jul 9, 2013·Proceedings of the National Academy of Sciences of the United States of America·Roger Y Tsien
Aug 3, 2000·Neuroreport·D Viggiano
Feb 21, 2004·Nature Reviews. Neuroscience·Ralf Kleene, Melitta Schachner
Jan 27, 2017·Cerebral Cortex·Jeanelle ArizaVerónica Martínez-Cerdeño
Mar 7, 2021·International Journal of Molecular Sciences·Daniela Carulli, Joost Verhaagen

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