Molecular identification and antibacterial properties of an ericoid associated mycorrhizal fungus

BMC Microbiology
O R AdeoyoJ F Dames

Abstract

The quest for novel sources of antibacterial compounds have necessitated the inclusion of ericoid mycorrhizal fungi (ERM) commonly found within the root of ericaceous plants. Agar-well diffusion method was used to detect antibacterial activity and was followed by the microbroth diffusion method [minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)]. The results of the phytochemical screening indicated that only alkaloids, flavonoids, phenols, saponins, cardiac glycosides and terpenoids were present, while steroids and tannins were absent. The MIC of the extracts ranged between 2 and 16 mg/mL, and the lowest MIC was obtained with Staphylococcus aureus. Also, the result of the MBC study indicated that the fungal extract was most active at concentrations of 2 and 4 mg/mL against Bacillus subtilis and S. aureus, respectively. This bioassay showed, for the first time, antibacterial activity of L. incrustata against some bacterial species. Subsequently, ERM fungi should be given attention when searching for antimicrobial agents because they could provide a solution to solve problems associated with conventional disease treatments (i.e. pathogenic microorganisms resistance).

References

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Jul 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Koichiro TamuraSudhir Kumar
Jun 10, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Lillian BarrosIsabel C F R Ferreira
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Feb 21, 2016·Fungal Biology·Christine Bizabani, Joanna Felicity Dames
Mar 24, 2016·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura

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Citations

Nov 21, 2021·BMC Microbiology·Saeed Ullah KhattakSaima Ikram

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Datasets Mentioned

BETA
EU678437
MF374380
MG209608

Methods Mentioned

BETA
electrophoresis
X-Ray
PCR

Software Mentioned

molecular evolutionary genetics analysis
BLAST
Basic Local Alignment Search Tool ( BLAST )
Chromas Lite
ClustalX
Chromas
BioEdit

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