Molecular Identification of Diphyllobothrium nihonkaiense from 3 Human Cases in Heilongjiang Province with a Brief Literature Review in China

The Korean Journal of Parasitology
Weizhe ZhangXiaoli Zhang

Abstract

Human diphyllobothriasis is a widespread fish-borne zoonosis caused by the infection with broad tapeworms belonging to the genus Diphyllobothrium. In mainland China, so far 20 human cases of Diphyllobothrium infections have been reported, and the etiologic species were identified as D. latum and D. nihonkaiense based on morphological characteristics or molecular analysis. In the present study, proglottids of diphyllobothriid tapeworms from 3 human cases that occurred in Heilongjiang Province, China were identified as D. nihonkaiense by sequencing mitochondrial cytochrome c oxidase subunit I (cox1) and NADH dehydrogenase subunit 5 (nad5) genes. Two different cox1 gene sequences were obtained. One sequence showed 100% homology with those from humans in Japan. The remaining cox1 gene sequence and 2 different nad5 gene sequences obtained were not described previously, and might reflect endemic genetic characterizations. D. nihonkaiense might also be a major causative species of human diphyllobothriasis in China. Meanwhile, the finding of the first pediatric case of D. nihonkaiense infection in China suggests that infants infected with D. nihonkaiense should not be ignored.

References

Sep 7, 2005·International Journal for Parasitology·Jong-Yil ChaiAlan J Lymbery
Dec 2, 2005·Emerging Infectious Diseases·Jorge Luiz Mello SampaioTerry Dick
Feb 1, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Elizabeth J CareyDavid D Douglas
Feb 9, 2008·Emerging Infectious Diseases·Yves JacksonFrançois Chappuis
Jan 13, 2009·Clinical Microbiology Reviews·Tomás ScholzBarbara Wicht
May 16, 2009·Parasitology Research·Hiroshi Yamasaki, Toshiaki Kuramochi
Dec 8, 2009·The Korean Journal of Parasitology·Hyeong-Kyu JeonKeeseon S Eom
Oct 4, 2012·European Journal of Human Genetics : EJHG·Eyal ReinsteinStephen P Robertson
Jul 4, 2013·Technology in Cancer Research & Treatment·Yunzhou WuDeshan Li
Jan 23, 2014·Emerging Infectious Diseases·Shanhong ChenHiroshi Yamasaki
Dec 31, 2014·The Korean Journal of Parasitology·Hong-Ja KimMin Seo
Mar 10, 2015·The Korean Journal of Parasitology·Sang Hyun ParkJin Bong Kim

❮ Previous
Next ❯

Citations

Jul 25, 2017·Current Opinion in Infectious Diseases·Camille Webb, Miguel M Cabada
Jul 18, 2018·Emerging Infectious Diseases·Hiroshi IkunoHiroshi Yamasaki

❮ Previous
Next ❯

Datasets Mentioned

BETA
AB573405
EF420138
AB268585
AB781787

Methods Mentioned

BETA
PCR
electrophoresis

Software Mentioned

Mega
Clustal X

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.