PMID: 16507239Mar 2, 2006Paper

Molecular imaging by MRI

Current Cardiology Reports
Patrick M WinterGregory M Lanza

Abstract

The goal of molecular imaging is to detect pathologic biomarkers, which can lead to early recognition of diseases, better therapeutic management, and improved monitoring for recurrence. MRI is a particularly attractive method for molecular imaging applications, due to its noninvasive nature, outstanding signal to noise ratio, high spatial resolution, exceptional tissue contrast, and short imaging times. Site-specific MRI contrast agents have been developed to target biologic processes that occur early in the development of atherosclerotic plaques, including angiogenesis and lipid accumulation, or biosignatures that appear later, such as fibrin and tissue factor resulting from plaque rupture. Moreover, targeted contrast agents can also serve as drug delivery vehicles, combining diagnosis and therapy. If ultimately successful, these emerging molecular imaging agents and techniques will allow early disease recognition and quantification prompting therapeutic intervention before serious sequelae ensue.

References

Dec 7, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·X YuG M Lanza
Mar 5, 2003·Circulation·Samuel A Wickline, Gregory M Lanza
Jul 24, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Patrick M WinterGregory M Lanza
Mar 9, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Anne M MorawskiSamuel A Wickline
Jul 21, 2004·Trends in Cardiovascular Medicine·William P Fay
Dec 17, 2004·Journal of the American Chemical Society·Juan C FriasZahi A Fayad
Feb 8, 2005·Radiologic Clinics of North America·Edward J Delikatny, Harish Poptani
Aug 18, 2005·Academic Radiology·Patrick M WinterGregory M Lanza

❮ Previous
Next ❯

Citations

Sep 12, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Weibo CaiXiaoyuan Chen
Sep 23, 2008·Bioconjugate Chemistry·Paul J EndresThomas J Meade
Dec 30, 2009·Nano Letters·Lisa M ManusThomas J Meade
Jul 10, 2009·Chemical Communications : Chem Comm·Dipanjan PanGregory M Lanza
Aug 10, 2010·Nanoscale·Fengqin HuThomas J Meade
Aug 25, 2007·Nanomedicine·Willem J M MulderZahi A Fayad
Apr 30, 2009·Radiology·Marlies OostendorpWalter H Backes
Mar 10, 2009·Current Problems in Cardiology·Birgit KantorThomas C Gerber
Nov 21, 2015·Journal of Molecular Evolution·Cheng JinWeihong Tan
Oct 13, 2006·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Liz Warburton, Jonathan Gillard
Jun 24, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Marlies OostendorpWalter H Backes
Jul 1, 2006·Drug Discovery Today. Technologies·Steven R MeikleStephen E Rose
Mar 28, 2013·Journal of Medical Physics·Saeed ShanehsazzadehFariba Johari Daha
Mar 16, 2007·Expert Review of Medical Devices·Patrick M WinterGregory M Lanza
Sep 6, 2020·International Journal of Molecular Sciences·Gengqi LiuYumiao Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Related Papers

Radiology
R Weissleder, U Mahmood
Journal of Cellular Biochemistry. Supplement
Michael A KingFreek J Beekman
Toxicologic Pathology
Robert R MaronpotG Allan Johnson
© 2021 Meta ULC. All rights reserved