Molecular imaging probes derived from natural peptides

Natural Product Reports
C L CharronL G Luyt

Abstract

Covering: up to the end of 2015.Peptides are naturally occurring compounds that play an important role in all living systems and are responsible for a range of essential functions. Peptide receptors have been implicated in disease states such as oncology, metabolic disorders and cardiovascular disease. Therefore, natural peptides have been exploited as diagnostic and therapeutic agents due to the unique target specificity for their endogenous receptors. This review discusses a variety of natural peptides highlighting their discovery, endogenous receptors, as well as their derivatization to create molecular imaging agents, with an emphasis on the design of radiolabelled peptides. This review also highlights methods for discovering new and novel peptides when knowledge of specific targets and endogenous ligands are not available.

References

Nov 1, 1977·FEBS Letters·M Deschodt-LanckmanJ Christophe
Sep 1, 1992·Metabolism: Clinical and Experimental·P MarbachT Terasaki
Dec 15, 1992·Biochemical and Biophysical Research Communications·M MasudaT Murakami
Jan 1, 1991·Annual Review of Neuroscience·S Nakanishi
Jan 1, 1985·Journal of Neuro-oncology·J M AllenS R Bloom
Nov 1, 1987·Journal of Medicinal Chemistry·V J HrubyM F Hintz
May 1, 1985·Journal of Medicinal Chemistry·W L CodyM E Hadley
Jul 1, 1985·The Journal of Clinical Endocrinology and Metabolism·A Couvineau, M Laburthe
Jul 2, 1981·Nature·D F VeberR Hirschmann
Apr 2, 1984·Life Sciences·D F VeberA G Zacchei
Dec 8, 1983·Nature·T E AdrianJ M Polak
Sep 1, 1995·General Pharmacology·C A Maggi
Sep 26, 1995·Proceedings of the National Academy of Sciences of the United States of America·A J DanielsA Spaltenstein
Jan 1, 1994·Journal of Molecular Neuroscience : MN·G LillingI Gozes
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·S R NagallaE R Spindel
Apr 1, 1993·Physiological Reviews·M Otsuka, K Yoshioka
Jun 9, 1995·International Journal of Cancer. Journal International Du Cancer·I M HennigJ C Reubi
Mar 1, 1995·Trends in Pharmacological Sciences·D HoyerJ E Taylor
Jan 22, 1993·Regulatory Peptides·N P GerardC Gerard
May 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·T W MoodyI Gozes
Apr 1, 1993·European Journal of Nuclear Medicine·D J KwekkeboomS W Lamberts
Sep 1, 1995·Medicinal Research Reviews·G S KroogJ F Battey
Sep 1, 1995·International Journal of Peptide and Protein Research·D R BolinM O'Donnell
Dec 1, 1995·Cellular and Molecular Neurobiology·I GozesD E Brenneman
Apr 9, 1996·Regulatory Peptides·D Larhammar

❮ Previous
Next ❯

Citations

Jan 6, 2017·Journal of Peptide Science : an Official Publication of the European Peptide Society·Nathalie M GrobThomas L Mindt
Nov 9, 2017·Journal of Labelled Compounds & Radiopharmaceuticals·Simone Maschauer, Olaf Prante
Nov 28, 2017·Nature Communications·Simon ArnoldiniViola Vogel
Feb 8, 2018·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Aleksandra PekošakAlbert D Windhorst
Sep 7, 2018·Angewandte Chemie·Jens Rickmeier, Tobias Ritter
Jan 28, 2020·Journal of Peptide Science : an Official Publication of the European Peptide Society·Drishty SatpatiAshutosh Dash
Dec 24, 2018·Organic & Biomolecular Chemistry·William L TurnbullLeonard G Luyt
Sep 3, 2020·Chemical Science·Dongdong SuXueyun Gao
Dec 12, 2018·Advanced Materials·Weizhi Wang, Zhiyuan Hu
May 20, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Brendan J EvansJoanne F Jamie
Aug 13, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lisa-Maria RečnikThomas L Mindt
Apr 25, 2020·Bioorganic Chemistry·Fariba MalekiNourollah Sadeghzadeh
May 23, 2021·European Journal of Medicinal Chemistry·Syed Faheem Askari Rizvi, Haixia Zhang
Nov 27, 2018·Bioconjugate Chemistry·Ying ZhouLing Xi
Jan 6, 2018·Journal of the American Chemical Society·Stefan VerhoogVéronique Gouverneur
Nov 14, 2017·Journal of the American Chemical Society·Xing ChenE James Petersson
Dec 17, 2020·Bioconjugate Chemistry·Paweł KręciszPaweł Szymański
Oct 15, 2021·Nanotechnology·Chenlei WangYeteng Zhong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
E P Krenning, M de Jong
Methods : a Companion to Methods in Enzymology
Kim SerdonsGuy M Bormans
Expert Opinion on Drug Discovery
Kobra Omidfar, Maryam Daneshpour
© 2022 Meta ULC. All rights reserved