Aug 12, 2006

Molecular interactions between bacterial symbionts and their hosts

Cell
C Dale, Nancy A Moran

Abstract

Symbiotic bacteria are important in animal hosts, but have been largely overlooked as they have proved difficult to culture in the laboratory. Approaches such as comparative genomics and real-time PCR have provided insights into the molecular mechanisms that underpin symbiont-host interactions. Studies on the heritable symbionts of insects have yielded valuable information about how bacteria infect host cells, avoid immune responses, and manipulate host physiology. Furthermore, some symbionts use many of the same mechanisms as pathogens to infect hosts and evade immune responses. Here we discuss what is currently known about the interactions between bacterial symbionts and their hosts.

  • References94
  • Citations255

References

  • References94
  • Citations255

Citations

Mentioned in this Paper

Vertebrates
Pathologic Cytolysis
Embryo
Real-Time Polymerase Chain Reaction
Immune Response
Pathogenic Aspects
Gene Expression Regulation, Bacterial
Biochemical Pathway
ANK Repeat Domains
CDB2 gene

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