PMID: 9167560May 17, 1997Paper

Molecular investigation into outbreak of HIV in a Scottish prison

BMJ : British Medical Journal
D L YirrellA J Leigh Brown

Abstract

To support already established epidemiological links between inmates of Glenochil prison positive for HIV infection by using molecular techniques and thus provide evidence of the extent of acquisition during a recent outbreak of the disease resulting from needle sharing. To identify possible sources of the outbreak, and to demonstrate the ability of the methodology to make further links beyond the original outbreak. Viral sequences obtained from the blood of HIV positive prisoners previously identified by standard epidemiological methods were compared with each other and with sequences from other Scottish patients. Glenochil prison for men, central Scotland. Adult inmates and their possible contacts. Phylogenetic analysis of viral sequences in two different genomic regions showed that 13 of the 14 HIV positive prisoners had been infected from a common source. Previous research had shown that six of these had acquired their infection in Glenochil; molecular evidence suggests that more than double this number were infected while incarcerated. Virus from two long term HIV positive patients who were in the prison at the time of the outbreak but who were not identified in the original or subsequent surveys was sufficiently different...Continue Reading

Citations

Apr 10, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Mauro PistelloMauro Bendinelli
Dec 13, 2000·International Journal for Parasitology·D J Conway, C Roper
Jan 1, 1999·Forensic Science International : Synergy·T KorteT Seppälä
Jul 8, 2011·AIDS Research and Human Retroviruses·Ludimila Paula Vaz CardosoMariane Martins de Araújo Stefani
Jul 30, 2005·AIDS·Davey M SmithSusan J Little
Sep 27, 2005·AIDS·Philippe LemeyAnne-Mieke Vandamme
May 4, 2012·AIDS·Ronald J LubelchekDavid E Barker
Apr 9, 2005·Journal of Clinical Microbiology·N A SaundersI Tatt
Nov 17, 2001·BMJ : British Medical Journal·S M Bird, A J Brown
Feb 7, 2001·Sexually Transmitted Infections·D L YirrellG Codere
Mar 18, 2006·Harm Reduction Journal·Evan WoodThomas Kerr
Mar 21, 2008·PLoS Medicine·Fraser LewisAndrew J Leigh Brown
May 18, 2006·Emerging Infectious Diseases·Abe MacherDavid Wheeler
Jul 13, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Iain D TattJohn V Parry
Apr 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Samiran PandaMohan D Gupte
Mar 21, 2012·Virus Research·Apostolos BeloukasDimitrios Paraskevis
Jun 18, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·D ParaskevisA Hatzakis
Oct 9, 2004·New Genetics and Society·Garrath Williams, Doris Schroeder
Apr 7, 2007·AIDS Research and Human Retroviruses·Sonia ResikRonald Swanstrom
Aug 19, 2003·AIDS Research and Human Retroviruses·H BredellL Morris
Jun 29, 2001·AIDS Research and Human Retroviruses·A HaymanP Balfe
Aug 17, 2006·AIDS Research and Human Retroviruses·Magdi Darwish SaadJean Kirkland Carr
Dec 28, 2018·The Journal of Infectious Diseases·Huldrych F Günthard, Roger Kouyos
Mar 19, 2019·Current Opinion in HIV and AIDS·Joel O WertheimArt F Y Poon
Nov 19, 2002·Journal of Medical Microbiology·H BirleyG B Wyatt
Dec 28, 2017·AIDS·Ana B AbecasisAnne-Mieke Vandamme
Oct 20, 2020·Chinese Medical Journal·Zhi-Long DongFan Lyu
Dec 5, 2020·Chinese Medical Journal·Zhi-Long DongFan Lyu
Jun 24, 2021·Open Forum Infectious Diseases·Britt SkaathunJoel O Wertheim

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