Molecular makeup of HIV-1 envelope protein

International Reviews of Immunology
V VeljkovicR Metlas

Abstract

A broad range of structural, functional, and immunological similarities between HIV-1 gp120 and human proteins, especially those participating in immune responses, highlight gp120 as a pleiotropic protein that can in different ways affect many important functions of the human immune system. Here we described some of these properties of HIV-1 gp120 that represent the main obstacle in the development of effective and safe AIDS vaccine.

References

May 11, 1992·Nucleic Acids Research·A Bairoch, B Boeckmann
Jan 1, 1992·Vox Sanguinis·C SüsalG Opelz
Mar 1, 1991·AIDS Research and Human Retroviruses·D M AboulafiaD J Slamon
Jan 1, 1991·Progress in Neuro-psychopharmacology & Biological Psychiatry·M R RuffT P Bridge
Dec 1, 1990·AIDS Research and Human Retroviruses·D W Archibald, G A Cole
Sep 1, 1990·Journal of Neuroimmunology·Y YiangouH Festenstein
Jul 1, 1989·Journal of Neuroimmunology·S PaulS de la Rocha
Jul 22, 1989·Lancet·T P BridgeF K Goodwin
May 1, 1985·IEEE Transactions on Bio-medical Engineering·V VeljkovićD Lalović
Oct 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A Tutter, R Riblet
Jan 17, 1987·Lancet·L WetterbergC Pert
Jul 16, 1985·Biochemical and Biophysical Research Communications·S PaulS I Said
Jun 1, 1985·The Australian Journal of Experimental Biology and Medical Science·P A Drew, D J Shearman
Jan 15, 1974·Biochemistry·P Y Chou, G D Fasman
Apr 14, 1983·Nature·S Tonegawa

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