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Molecular mechanism of inhibition of firefly luminescence by local anesthetics

Proceedings of the National Academy of Sciences of the United States of America

Feb 1, 1976

Issaku UedaH Eyring

PMID: 1759

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Abstract

The kinetics of the action of local anesthetics upon firefly luciferin and luciferase systems is presented. Clinical concentrations of local anesthetics inhibited this ATP-induced luminescence in a dose-dependent manner. From the effects of temperature and pH upon the inhibitory action ...read more

Mentioned in this Paper

Phosphorescent Measurements
Luciferases
Local Anesthetics
Ligands
Order Coleoptera
Firefly Luciferin
Anesthesiology
Dose-Response Relationship, Drug
Metabolic Inhibition
Pontocaine
Paper Details
References
    • References13
    • Citations31
    • References13
    • Citations31
  • Molecular mechanism of inhibition of firefly luminescence by local anesthetics

    Proceedings of the National Academy of Sciences of the United States of America

    Feb 1, 1976

    Issaku UedaH Eyring

    PMID: 1759

    DOI:

    Abstract

    The kinetics of the action of local anesthetics upon firefly luciferin and luciferase systems is presented. Clinical concentrations of local anesthetics inhibited this ATP-induced luminescence in a dose-dependent manner. From the effects of temperature and pH upon the inhibitory action ...read more

    Mentioned in this Paper

    Phosphorescent Measurements
    Luciferases
    Local Anesthetics
    Ligands
    Order Coleoptera

    Related Papers

    Paper Details
    References
    • References13
    • Citations31
    • References13
    • Citations31
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