PMID: 8588739Dec 1, 1995Paper

Molecular mechanisms of endotoxin activity

Archives of Microbiology
J SchletterE T Rietschel

Abstract

Endotoxin (lipopolysaccharide, LPS), a constituent of the outer membrane of the cell wall of gram-negative bacteria, exerts a wide variety of biological effects in humans. This review focuses on the molecular mechanisms underlying these activities and discusses structure-function relationships of the endotoxin molecule, its interaction with humoral and cellular receptors involved in cell activation, and transmembrane and intracellular signal transduction pathways.

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Citations

Jun 15, 2005·Pulmonary Pharmacology & Therapeutics·Oguz KokselArzu Kanik
Feb 23, 2000·FEMS Immunology and Medical Microbiology·Y AsaiT Ogawa
Apr 3, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Suwannee UthaisangsookSoichi Haraguchi
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Apr 26, 2012·Proceedings of the National Academy of Sciences of the United States of America·Umeharu OhtoToshiyuki Shimizu
Oct 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ida PacielloMaria Lina Bernardini
Jun 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Takako KizakiHideki Ohno
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·K D Poss, S Tonegawa
Oct 12, 2012·The Journal of Biological Chemistry·Umeharu OhtoToshiyuki Shimizu
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