Molecular Mechanisms Regulating the Dendritic Development of Newborn Olfactory Bulb Interneurons in a Sensory Experience-Dependent Manner

Frontiers in Neuroscience
Sei-Ichi YoshiharaAkio Tsuboi

Abstract

Inhibitory interneurons in the olfactory bulb are generated continuously throughout life in the subventricular zone and differentiate into periglomerular and granule cells. Neural circuits that undergo reorganization by newborn olfactory bulb interneurons are necessary for odor detection, odor discrimination, olfactory memory, and innate olfactory responses. Although sensory experience has been shown to regulate development in a variety of species and in various structures, including the retina, cortex, and hippocampus, little is known about how sensory experience regulates the dendritic development of newborn olfactory bulb interneurons. Recent studies revealed that the 5T4 oncofetal trophoblast glycoprotein and the neuronal Per/Arnt/Sim domain protein 4 (Npas4) transcription factor regulate dendritic branching and dendritic spine formation, respectively, in olfactory bulb interneurons. Here, we summarize the molecular mechanisms that underlie the sensory input-dependent development of newborn interneurons and the formation of functional neural circuitry in the olfactory bulb.

References

Jan 15, 1990·International Journal of Cancer. Journal International Du Cancer·N Hole, P L Stern
Jan 1, 1990·British Journal of Cancer·P J SouthallP L Stern
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·K M GuthrieC Gall
Nov 15, 1996·Science·L C Katz, C J Shatz
Mar 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·G GheusiP M Lledo
Nov 21, 2001·Nature Reviews. Neuroscience·J R Sanes, J W Lichtman
Apr 22, 2003·Nature Neuroscience·Alan CarletonPierre-Marie Lledo
Oct 11, 2003·Mechanisms of Development·Miki TsukadaGregor Eichele
Oct 24, 2003·The Journal of Comparative Neurology·Jason P BrownH Georg Kuhn
Mar 23, 2004·Nature Neuroscience·Armen SaghatelyanPierre-Marie Lledo
Sep 24, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Emeka EnwereSamuel Weiss
Jan 6, 2005·The Journal of Biological Chemistry·Miki TsukadaGregor Eichele
Jun 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Masahiro Yamaguchi, Kensaku Mori
Jun 25, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Katie M BarrowPeter L Stern
Dec 6, 2005·The European Journal of Neuroscience·Christelle Rochefort, Pierre-Marie Lledo
Aug 23, 2006·Nature Reviews. Neuroscience·Jess Nithianantharajah, Anthony J Hannan
Aug 26, 2006·Molecular and Cellular Neurosciences·Polloneal J OcbinaFrancis G Szele
Oct 13, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mariana AlonsoPierre-Marie Lledo
Jul 8, 2008·Trends in Neurosciences·Pierre-Marie LledoArturo Alvarez-Buylla
Sep 2, 2008·Nature Neuroscience·Itaru ImayoshiRyoichiro Kageyama
Sep 26, 2008·Nature·Yingxi LinMichael E Greenberg
Oct 24, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mariana AlonsoPierre-Marie Lledo
Nov 22, 2008·Cold Spring Harbor Symposia on Quantitative Biology·A Alvarez-BuyllaF T Merkle
Jan 9, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yoav LivnehAdi Mizrahi
Jun 13, 2009·The European Journal of Neuroscience·Germain U BustoAnne Didier
Jul 21, 2009·Progress in Neurobiology·Mary C Whitman, Charles A Greer
Sep 9, 2009·Development·Renée van Amerongen, Roel Nusse
Sep 25, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wolfgang KelschCarlos Lois
Dec 4, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Patrizia PanzanelliJean-Marc Fritschy
Dec 4, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Vincent Breton-ProvencherArmen Saghatelyan
Dec 17, 2009·Current Opinion in Neurobiology·Yoav Adam, Adi Mizrahi
Mar 11, 2010·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·S SultanA Didier
Mar 18, 2010·The Journal of Comparative Neurology·Pierre-Olivier Bastien-DionneArmen Saghatelyan
Apr 2, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·John W CaveHarriet Baker
Feb 11, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sophie Scotto-LomasseseIsabelle Caillé
Mar 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Priit PruunsildTõnis Timmusk
Apr 8, 2011·Annual Review of Neuroscience·Kensaku Mori, Hitoshi Sakano
May 4, 2011·Proceedings of the National Academy of Sciences of the United States of America·Masayuki SakamotoRyoichiro Kageyama

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Citations

Jan 1, 2020·The Journal of Comparative Neurology·Colin M WakehamCatherine W Morgans
Apr 26, 2018·Frontiers in Neuroanatomy·Anna-Maria MaierJörg Strotmann
Aug 17, 2019·Frontiers in Cellular Neuroscience·Yuka TakahashiAkio Tsuboi
Jul 24, 2018·Frontiers in Molecular Neuroscience·Hiroo TakahashiAkio Tsuboi

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