PMID: 3753614Jan 1, 1986Paper

Molecular mimicry: frequency of reactivity of monoclonal antiviral antibodies with normal tissues

Journal of Virology
J SrinivasappaA L Notkins

Abstract

More than 600 monoclonal antiviral antibodies made against 11 different viruses were screened against 14 different organs from normal uninfected mice. Of these antiviral antibodies, 21, or approximately 3.5%, reacted with specific cells in these organs. Several of these antibodies were of the multiple-organ-reactive type and recognized antigens in more than one organ. It was concluded that the reactivity of monoclonal antiviral antibodies with normal tissues is a common phenomenon.

References

Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·T J Wiktor, H Koprowski
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·G P RiceM B Oldstone
Jul 1, 1982·The American Journal of Tropical Medicine and Hygiene·E A HenchalW E Brandt
Apr 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·R S FujinamiH Koprowski
Jul 7, 1983·Nature·M V HaspelA L Notkins
Jul 28, 1983·The New England Journal of Medicine·J SatohA L Notkins
Mar 18, 1982·Nature·D Lane, H Koprowski

❮ Previous
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Citations

Oct 1, 1991·Clinical and Experimental Immunology·K W BeiselB S Prabhakar
Jan 1, 1990·Autoimmunity·A P Weetman, L K Borysiewicz
Jan 1, 1990·Scandinavian Journal of Rheumatology. Supplement·P Ivanyi
Jul 1, 1987·Diabetic Medicine : a Journal of the British Diabetic Association·A Lernmark
Jul 17, 1998·Annals of Neurology·M C LevinS Jacobson
Aug 18, 1999·Immunological Reviews·M S Horwitz, N Sarvetnick
Oct 6, 2005·Nature Reviews. Microbiology·J Lindsay WhittonRalph Feuer
Jan 19, 2006·Clinical Microbiology Reviews·Robert S FujinamiJ Lindsay Whitton
Sep 29, 2006·The Journal of Small Animal Practice·M ZarfossA Delahunta
Oct 8, 2013·Evolution; International Journal of Organic Evolution·Amy Hurford, Troy Day
Jun 12, 1989·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·P M ColmanR G Webster
Oct 1, 1993·AIDS Research and Human Retroviruses·M EddlestonM B Oldstone
Jan 1, 1996·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·T J PalkerA Vahlne
Jun 14, 2000·Journal of Virology·M MeiteJ P Coutelier
Feb 27, 2008·International Reviews of Immunology·Raghavan Raju, Christiane S Hampe
Dec 29, 2004·Autoimmunity·J Lindsay Whitton, Ralph Feuer
Sep 6, 2012·International Journal of Molecular Sciences·Miroslava Jankovic, Ninoslav Mitic
Apr 17, 2012·Current Opinion in Rheumatology·Urs ChristenMatthias G von Herrath
Jul 4, 2020·Nature Reviews. Disease Primers·Terry F DaviesGeorge J Kahaly
Apr 1, 1997·Immunology and Cell Biology·J M Davies
Jan 1, 1995·Genetica·R S Root-Bernstein, S H DeWitt
Jan 1, 1989·Immunologic Research·R S Fujinami, M B Oldstone
Jun 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·J FohlmanS Huber
Jan 1, 1995·Viral Immunology·A D Cohen, Y Shoenfeld
Oct 8, 1998·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·M B Oldstone
Apr 12, 2007·Clinical Reviews in Allergy & Immunology·Miri BlankYehuda Shoenfeld
Nov 3, 2009·Lupus·N Agmon-LevinY Shoenfeld
Mar 24, 2005·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·F García-VallejoO Tamayo
Mar 19, 2014·Antioxidants & Redox Signaling·Federico CarboneFabrizio Montecucco
Oct 1, 2013·Veterinary Pathology·J M Ward, J E Rehg
Jan 1, 1991·International Reviews of Immunology·C NickersonC David
Mar 17, 2011·PloS One·Philipp LudinPascal Mäser
Apr 17, 2012·Immunological Reviews·Tyani D Chan, Robert Brink
Apr 4, 2014·Monoclonal Antibodies in Immunodiagnosis and Immunotherapy·Michael B A Oldstone

❮ Previous
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