Molecular neurobiology of human cognition

Neuron
Edwin J Weeber, J David Sweatt

Abstract

Recent studies into human mental retardation syndromes have given new insights into the molecular underpinnings of human cognitive processing, in particular into mechanisms likely to contribute to learning and memory. In this minireview, we present an overview of one signal transduction cascade that has garnered attention of late in this context, the ras/ERK/CREB pathway. We focus on this cascade because of recent exciting discoveries concerning the basis of neurofibromatosis type 1 (NF1) mental retardation, which link cognitive defects in this syndrome to disruptions of ras and its intracellular targets.

References

Jun 22, 2000·Nature Neuroscience·H HusiS G Grant
Jun 21, 2001·Proceedings of the National Academy of Sciences of the United States of America·W T GreenoughI J Weiler
Jan 15, 2002·Nature Neuroscience·Jiayuan TongYi Zhong

❮ Previous
Next ❯

Citations

Jul 12, 2002·Journal of Neuroscience Research·Marjorie A ArianoMichael S Levine
Mar 21, 2007·Journal of Biomedical Science·Yi-Ping Hsueh
Feb 14, 2003·Current Neurology and Neuroscience Reports·Tena L Rosser, Roger J Packer
May 4, 2004·Brain Research Bulletin·Whitney Freeman, A Jennifer Morton
Jun 6, 2003·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Michael V Johnston
May 8, 2009·Chemical Society Reviews·Jeremy P E Spencer
Sep 26, 2013·Proceedings of the National Academy of Sciences of the United States of America·Kiriana K CowansageJoseph E Ledoux
Aug 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Rusiko BourtchouladzeTim Tully
Mar 30, 2010·Annual Review of Neuroscience·C ShilyanskyA J Silva
May 29, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Aurelie ContrepasGenevieve Nguyen
Feb 27, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Anastasios MoressisEfthimios M C Skoulakis
Apr 24, 2013·The Journal of Endocrinology·Hyunju ChungSeungjoon Park
Feb 28, 2006·Nature Genetics
Jan 11, 2005·Médecine sciences : M/S·Isabelle M Mansuy
Jul 9, 2010·Frontiers in Neuroendocrinology·Tibor Hajszan, Csaba Leranth
Mar 9, 2010·Differentiation; Research in Biological Diversity·Neeti SharmaSharmila A Bapat
Feb 16, 2016·Neuroscience·M AsherM Cvetanovic
Mar 19, 2015·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Ivayla ApostolovaRalph Buchert
Oct 22, 2008·Neurobiology of Disease·Sebastiano CavallaroBen A Oostra
Aug 5, 2008·Neuropharmacology·F Josef van der StaayMartin Hendrix
Jan 8, 2005·American Journal of Medical Genetics. Part a·Patricia G Wheeler, Ab Sadeghi-Nejad
Jan 13, 2009·American Journal of Medical Genetics. Part a·Laura CesariniGiuseppe Zampino
Nov 28, 2006·Journal of Cellular and Molecular Medicine·Guy FroyenPeter Marynen
Oct 20, 2010·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·George S Zubenko, Hugh B Hughes
Jan 25, 2014·American Journal of Medical Genetics. Part a·Paolo AlfieriStefano Vicari
Jul 26, 2014·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·George S ZubenkoBruce M Cohen
May 21, 2011·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·George S Zubenko, Hugh B Hughes
May 18, 2004·Brain Research. Brain Research Reviews·Kenji HashimotoMasaomi Iyo
May 11, 2005·Progress in Neurobiology·Iryna M Ethell, Elena B Pasquale
Oct 29, 2003·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·George S ZubenkoMary L Marazita
Dec 19, 2003·Annals of Neurology·Ying-Chao ChangChao-Ching Huang
Nov 28, 2008·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·George S ZubenkoMiguel Estevez
May 29, 2009·Journal of Neuroscience Research·Chang Sin ParkShao-Jun Tang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.

Related Papers

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
George S Zubenko, Hugh B Hughes
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
Brion S MaherGeorge S Zubenko
© 2022 Meta ULC. All rights reserved