PMID: 11898394Mar 20, 2002Paper

Molecular, structural, and cellular biology of follitropin and follitropin receptor

Vitamins and Hormones
James A DiasAnja Schmidt

Abstract

Follitropin and the follitropin receptor are essential for normal gamete development in males and females. This review discusses the molecular genetics and structural and cellular biology of the follitropin/follitropin receptor system. Emphasis is placed on the human molecules when possible. The structure and regulation of the genes for the follitropin beta subunit and the follitropin receptor is discussed. Control of systemic and cellular protein levels is explained. The structural biology of each protein is described, including protein structure, motifs, and activity relationships. Finally, the follitropin/follitropin receptor signal transduction system is discussed.

Citations

Jun 5, 2007·Thyroid : Official Journal of the American Thyroid Association·Jane SandersBernard Rees Smith
Nov 13, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Ping YanJintao Li
Mar 14, 2013·BioMed Research International·Katarzyna Kossowska-Tomaszczuk, Christian De Geyter
Jul 10, 2018·Endocrinology·Alfredo Ulloa-AguirrePascale Crépieux
Oct 22, 2005·Preparative Biochemistry & Biotechnology·Hitendra S ChandK Muralidhar
Oct 24, 2013·The Journal of Obstetrics and Gynaecology Research·Xiaoyan ZhangCongjian Xu
May 26, 2018·Endocrinology·Selvaraj NatarajaStephen Palmer
Aug 27, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·Sabine CostagliolaGilbert Vassart
Feb 5, 2008·Endocrine·Alfredo Ulloa-AguirreJames A Dias
Aug 27, 2010·Biology of Reproduction·Jitu W GeorgeLeslie L Heckert
Aug 22, 2014·Biology of Reproduction·T Rajendra Kumar
Nov 6, 2015·Frontiers in Endocrinology·Mariusz W Szkudlinski
Jun 1, 2015·Iranian Journal of Biotechnology·Zahra Elyasi GorjiMohammad Hossein Sanati
Oct 19, 2016·Molecular Pharmacology·Alfredo Ulloa-Aguirre, Teresa Zariñán
Jan 22, 2005·Nature·Qing R Fan, Wayne A Hendrickson
Jan 22, 2005·Nature·James A Dias
Mar 18, 2006·Molecular Endocrinology·Joost Van DurmeGilbert Vassart
May 28, 2009·Journal of Separation Science·Marlene Zandian, Alois Jungbauer
Apr 27, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Paolo OnoriEugenio Gaudio
Dec 18, 2018·Frontiers in Endocrinology·Alfredo Ulloa-AguirreJames A Dias
Aug 11, 2010·Biomedit︠s︡inskai︠a︡ khimii︠a︡·A O Shpakov, E A Shpakova
Dec 1, 2020·The FEBS Journal·Antara A BanerjeeSmita D Mahale
Mar 2, 2021·Journal of Agricultural and Food Chemistry·Rongmao HuaQingwang Li
Jan 29, 2011·Fertility and Sterility·Sunshin KimKyuBum Kwack

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