Molecular subtyping of feline immunodeficiency virus from domestic cats in Australia

Australian Veterinary Journal
R KannJ Meers

Abstract

To determine the prevalent subtypes of feline immunodeficiency virus (FIV) present in the domestic cat population of Australia. Blood samples were collected from 41 FIV antibody positive cats from four cities across Australia. Following DNA extraction, polymerase chain reaction (PCR) was performed to amplify the variable V3-V5 region of the envelope (env) gene. Genotypes were assessed by direct sequencing of PCR products and comparison with previously reported FIV sequences. Phylogenetic analysis allowed classification of the Australian sequences into the appropriate subtype. Of the 41 FIV samples, 40 were found to cluster with previously reported subtype A isolates, whilst the remaining sample grouped within subtype B. Subtype A was found to be the predominant FIV subtype present in Australia, although subtype B was also found. These results broaden our knowledge of the genetic diversity of FIV and the associated implications for preventative, diagnostic and therapeutic approaches.

References

Jun 1, 1990·Nihon juigaku zasshi. The Japanese journal of veterinary science·T Ishida, I Tomoda
May 1, 1989·Veterinary Immunology and Immunopathology·N C PedersenH Hansen
Aug 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R L TalbottJ H Elder
Oct 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R A OlmstedP R Johnson
Dec 1, 1994·AIDS Research and Human Retroviruses·S OkadaJ K Yamamoto
Sep 1, 1996·The Journal of General Virology·M R PecoraroT Mikami
Jan 1, 1996·Archives of Virology·M T Kyaw-Tanner, W F Robinson
Aug 1, 1997·Vaccine·J S ElyarJ K Yamamoto
Mar 19, 1999·The Journal of Veterinary Medical Science·M UemaE Takahashi
May 22, 2002·Archives of Virology·A DuarteM Fevereiro
Aug 2, 2002·The Lancet Infectious Diseases·Michael M ThomsonRafael Nájera
Jun 26, 2004·The Journal of General Virology·F Reggeti, D Bienzle
Feb 3, 2005·Journal of Feline Medicine and Surgery·Ruiyu PuJanet K Yamamoto

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Citations

Jun 2, 2009·Journal of Feline Medicine and Surgery·Margaret J HosieMarian C Horzinek
Dec 7, 2007·New Zealand Veterinary Journal·R K C KannR J G Zwijnenberg
Oct 16, 2015·Comparative Immunology, Microbiology and Infectious Diseases·Mark E WestmanJacqueline M Norris
Oct 2, 2008·Australian Veterinary Journal·D Iwata, S A Holloway
Feb 24, 2015·Retrovirology·Paweł M BęczkowskiMargaret J Hosie
Jun 7, 2013·Journal of Feline Medicine and Surgery·Janine Chang-Fung-MartelRichard Squires
Jul 18, 2015·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Rebecca Penrose WilkesHwa-Tang Thomas Wang
Feb 16, 2007·Australian Veterinary Journal·M J Hosie, J A Beatty
Jul 7, 2021·Comparative Immunology, Microbiology and Infectious Diseases·Dilek MuzMustafa Necati Muz

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