Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies

World Journal of Gastroenterology : WJG
Tasuku Matsuoka, Masakazu Yashiro

Abstract

Pancreatic cancer is the fourth most common cause of cancer deaths worldwide. Although recent therapeutic developments for patients with pancreatic cancer have provided survival benefits, the outcomes for patients with pancreatic cancer remain unsatisfactory. Molecularly targeted cancer therapy has advanced in the past decade with the use of a number of pathways as candidates of therapeutic targets. This review summarizes the molecular features of this refractory disease while focusing on the recent clinical and experimental findings on pancreatic cancer. It also discusses the data supporting current standard clinical outcomes, and offers conclusions that may improve the management of pancreatic cancer in the future.

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Citations

Apr 22, 2017·World Journal of Gastroenterology : WJG·Chandra DiwakarlaDesmond Yip
Jul 22, 2019·Journal of Personalized Medicine·Matthew LoftPeter Gibbs
Mar 19, 2021·Expert Opinion on Emerging Drugs·Jasmeet KaurVaibhav Sahai
Dec 4, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Xiaochen WuChuanlong Guo
Oct 8, 2020·Molecular Therapy Oncolytics·Sharavan Ramachandran, Sanjay K Srivastava

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