Molecular typing and antimicrobial susceptibility profiles of Campylobacter jejuni isolates from north China

Journal of Medical Microbiology
Maojun ZhangJianzhong Zhang

Abstract

To obtain the genotype and antimicrobial susceptibility profiles of Campylobacter jejuni isolates from north China, 93 C. jejuni isolates (56 isolates from patients with diarrhoea, 7 isolates from Guillain-Barré syndrome patients and 30 isolates from chicken stools) were selected for multilocus sequence typing (MLST), PFGE and drug resistance testing. A total of 49 sequence types (STs) were identified from the entire panel of 93 C. jejuni isolates. Fifty-six isolates belonged to 14 clonal complexes, while 37 isolates could not be assigned to any known clonal complex. The most frequently observed clonal complexes were ST-21 (11 isolates), ST-353 (10 isolates) and ST-443 (6 isolates). Fifty-three PFGE SmaI patterns were identified among 93 isolates. No erythromycin-, gentamicin- or streptomycin-resistant isolates were found among the 44 strains isolated in 2008. Resistance to nalidixic acid, levofloxacin and ciprofloxacin was observed in 100 % (44/44) of the tested isolates. This study has shown the genetic characteristics of C. jejuni isolates in north China. In addition, overlapping clonal groups were defined by both MLST and PFGE for C. jejuni human and chicken isolates.

References

Jan 1, 1983·Epidemiologic Reviews·M J BlaserR A Feldman
Nov 23, 1995·The New England Journal of Medicine·J H ReesR A Hughes
Jun 1, 1997·Archives of Disease in Childhood·E A GoddardA C Argent
Jul 17, 1998·Clinical Microbiology Reviews·I NachamkinT Ho
Jul 21, 1998·Annals of the New York Academy of Sciences·K A SheikhG M McKhann
Jan 4, 2001·Journal of Clinical Microbiology·K E DingleM C Maiden
Jun 28, 2001·Journal of Clinical Microbiology·C FitzgeraldP I Fields
Dec 21, 2006·Emerging Infectious Diseases·Will SopwithEric Bolton

❮ Previous
Next ❯

Citations

Aug 18, 2012·BMC Infectious Diseases·Simon PollettMatthew Kasper
Mar 29, 2014·International Journal of Food Microbiology·Secil AbayNurhan Ertas
Sep 13, 2013·Journal of Clinical Microbiology·Margaret A DavisThomas E Besser
Oct 22, 2016·Avian Pathology : Journal of the W.V.P.A·Xiaoyan ZhangXinan Jiao
Mar 25, 2015·The American Journal of Tropical Medicine and Hygiene·Corinne N ThompsonStephen Baker
Mar 22, 2016·Journal of Applied Microbiology·A ZhangM Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Campylobacteriosis

Campylobacteriosis is caused by the bacteria Campylobacter jejuni and is a common cause of gastroenteritis in humans. Discover the latest research on Campylobacteriosis here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Campylobacteriosis (ASM)

Campylobacteriosis is caused by the bacteria Campylobacter jejuni and is a common cause of gastroenteritis in humans. Discover the latest research on Campylobacteriosis here.