Molecular Typing of Syphilis-Causing Strains Among Human Immunodeficiency Virus-Positive Patients in Antwerp, Belgium

Sexually Transmitted Diseases
Lenka MikalováDavid Šmajs

Abstract

Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.

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Citations

Sep 13, 2019·Future Microbiology·Candela Fernández-NavalJuliana Esperalba
Sep 10, 2020·International Journal of STD & AIDS·Chris KenyonKristien Wouters
Jun 9, 2020·Acta Clinica Belgica·Vicky JespersWim Vanden Berghe

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