Molecularly imprinted polymer based diffusive gradients in thin-films for in situ selective sampling and determination of ciprofloxacin

Journal of Separation Science
Yanan LiJianrong Li

Abstract

A technique of diffusive gradients in thin films with ciprofloxacin-molecularly imprinted polymers as the binding agent was developed for in situ selective sampling and measurement of ciprofloxacin in water. The ciprofloxacin uptake by the method increased linearly with time (r2  = 0.998) with a recovery of 96.8% in synthetic solution. The method performance was not dependent on solution pH over the pH range of 2-11 and ionic strength range from 1 × 10-4 to 0.5 mol/L sodium nitrate. The binding agent has a higher adsorption affinity for ciprofloxacin than for other drug residues, such as norfloxacin, chloramphenicol, and malachite green. The concentration of ciprofloxacin in river water determined by this method was 0.52 ± 0.3 μg/L, and the recoveries of ciprofloxacin were 96.1-102.0%.

References

Feb 13, 2007·Chemosphere·M D HernandoA R Fernández-Alba
Apr 28, 2012·Journal of Environmental Monitoring : JEM·Chang-Er ChenKevin C Jones
Jan 3, 2013·Journal of Separation Science·Won Jo CheongFaiz Ali
Oct 17, 2016·Journal of Pharmaceutical and Biomedical Analysis·O SzerkusM J Markuszewski
Oct 22, 2017·The Science of the Total Environment·Huaijun XieChengzhi Zhou

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Citations

Aug 20, 2019·Water Environment Research : a Research Publication of the Water Environment Federation·Daniel D SnowJonathan Brett Sallach

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