Molecularly imprinted polymers-A closer look at the control polymer used in determining the imprinting effect: A mini review.

Journal of Molecular Recognition : JMR
Elizabeth N Ndunda

Abstract

Molecular recognition displayed by naturally occurring receptors has continued to inspire new innovations aimed at developing systems that can mimic this natural phenomenon. Since 1930s, a technology called molecular imprinting for producing biomimetic receptors has been in place. In this technology, tailor made binding sites that selectively bind a given target analyte (also called template) are incorporated in a polymer matrix by polymerizing functional monomers and cross-linking monomers around a target analyte followed by removal of the analyte to leave behind cavities specific to the analyte. The success of the imprinting process is defined by two main figures of merit, that is, the imprinting factor, and selectivity, which are determined by comparing the amount of target analyte or structural analogue bound by the molecularly imprinted polymer (MIP) and the nonimprinted polymer (NIP). NIP is a control synthesized alongside the MIP but in the absence of the template. However, questions arise on whether these figures of merit are reliable measures of the imprinting effect because of the significant differences between the MIP and the NIP in terms of their physical and chemical characteristics. Therefore, this review critica...Continue Reading

References

Feb 18, 1993·Nature·G VlatakisK Mosbach
Nov 2, 2005·Advanced Drug Delivery Reviews·David A Spivak
Jan 6, 2006·Journal of Molecular Recognition : JMR·Cameron AlexanderMichael J Whitcombe
Aug 30, 2008·Water Research·Zhang Zhongbo, Jiangyong Hu
Apr 28, 2009·Biosensors & Bioelectronics·Santwana PradhanR Vijayaraghavan
Jun 21, 2013·Chemical Communications : Chem Comm·Serena AmbrosiniBernadette Tse Sum Bui
Jan 9, 2014·International Journal of Molecular Sciences·Jun ChenYu-Ping Zhang
Jun 5, 2014·Journal of Molecular Recognition : JMR·Di SongKen D Shimizu
Jun 12, 2014·Analytical and Bioanalytical Chemistry·Xuan SunZhao-Sheng Liu
Aug 12, 2014·Journal of Chromatography. a·Shima N N S HashimMilton T W Hearn
Nov 13, 2015·Environmental Science. Processes & Impacts·Elizabeth N NdundaBoris Mizaikoff
Feb 13, 2016·Nature Protocols·Francesco CanfarottaSergey Piletsky
Mar 2, 2017·Sensors·Sibel Emir DiltemizRıdvan Say
Feb 23, 2018·Chemistry Central Journal·Showkat Ahmad BhawaniMohammad Nasir Mohammad Ibrahim
Oct 28, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Bettina PluharBoris Mizaikoff

❮ Previous
Next ❯

Citations

Apr 26, 2021·Biosensors & Bioelectronics·Hassan Karimi-MalehAmani Al-Othman
Apr 30, 2021·Biosensors & Bioelectronics·Pedro V V RomanholoLivia F Sgobbi
Jun 3, 2021·International Journal of Molecular Sciences·Vilma RatautaiteArunas Ramanavicius
Aug 8, 2021·Analytical Biochemistry·Noman NawazNazzatush Shimar Jamaludin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses
C Stewart-Amidei
© 2022 Meta ULC. All rights reserved