PMID: 19920650Apr 1, 1995Paper

Molteno implant versus trabeculectomy with adjunctive intreoperative mitomycin-C in high-risk glaucoma patients

Journal of Glaucoma
F E SayyadA El-Maghraby

Abstract

The Molteno implant is one of the most widely used drainage devices for the management of complicated glaucoma. Antiproliferative agents such as mitomycin-C (MMC) have markedly improved the outcome of glaucoma filtering surgery. This case control study compares the results of these two techniques in the management of high-risk glaucoma patients. Forty-three consecutive patients with complicated glaucoma who underwent glaucoma filtration surgery with intraoperative application of 0.3 mg/ml of MMC were matched with a control group of 43 glaucoma patients who previously had tube surgery using a single-plate Molteno drainage implant in most of the cases. Control patients were matched based on diagnostic group of glaucoma, the number of prior filtration surgeries, and patient age. All patients had a minimum follow-up time of 12 months. Intraocular pressure (IOP) +/- 21 mm Hg was achieved 6 months postoperatively in 34 patients (79.1%) with Molteno implant and in 38 (88.4%) treated with MMC (p < 0.2), and 12 months postoperatively in 26 (60.5%) and 35 (81.4%) patients, respectively (p < 0.03). Complications after Molteno implant included hypotony (20.9%), flat anterior chamber (11.6%). tube-cornea touch (6.9%), and tube exposure (4.7...Continue Reading

Citations

Apr 19, 2019·The Cochrane Database of Systematic Reviews·Valencia Hui Xian FooShamira A Perera

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