Monitoring bone morphogenetic protein-2 and -7, soluble receptor activator of nuclear factor-κB ligand and osteoprotegerin levels in the peri-implant sulcular fluid during the osseointegration of hydrophilic-modified sandblasted acid-etched and sandblasted acid-etched surface dental implants

Journal of Periodontal Research
D DolanmazS S Hakki

Abstract

The implant surface plays a major role in the biological response to titanium dental implants. The aim of this study was to investigate levels of soluble receptor activator of nuclear factor-κB ligand (sRANKL), osteoprotegerin (OPG), bone morphogenetic protein-2 (BMP-2) and -7 (BMP-7) in the peri-implant crevicular fluid (PICF) of different implants during the osseointegration period. Forty-seven patients (22 females and 25 males, mean age 47.34 ± 10.11) were included in this study. Forty-seven implants from two implant systems (group A1 (sandblasted acid-etched [SLA]-16), group A2 (hydrophilic-modified SLA [SLActive]-16), and group B (sandblasted acid-etched [SLA]-15) were placed using standard surgical protocols. PICF samples, plaque index, gingival index and probing depth measurements were obtained at 1 and 3 mo after surgery. PICF levels of sRANKL, OPG, BMP-2/-7 were analyzed by ELISA. No complications were observed during the healing period. No significant differences were observed in the PICF levels of sRANKL, OPG, BMP-2 and BMP-7 for all groups at any time point (p > 0.05). A significant decrease was observed in BMP-2 levels in group A1 (p < 0.05). A significant increase in BMP-7 levels was observed only for group A2 (p ...Continue Reading

References

Dec 1, 1987·Oral Microbiology and Immunology·A MombelliN P Land
Nov 1, 1967·Journal of Periodontology·H Löe
Mar 1, 1994·Clinical Oral Implants Research·R Mericske-SternA H Geering
Jan 1, 1996·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·K KieswetterB D Boyan
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·H YasudaT Suda
Jun 1, 1997·Periodontology 2000·Z SchwartzB D Boyan
May 25, 1999·Periodontology 2000·R K Schenk, D Buser
Jul 8, 1999·Biomaterials·T J WebsterR Bizios
Jul 6, 2000·Journal of Biomedical Materials Research·T J WebsterR Bizios
Mar 27, 2003·Periodontology 2000·Gareth S Griffiths
May 4, 2004·Biomaterials·Thomas J Webster, Jeremiah U Ejiofor
Jun 26, 2004·Journal of Dental Research·D BuserS G Steinemann
Jul 1, 2004·Journal of Biomedical Materials Research. Part a·Ali K RefaiJ Douglas Waterfield
Aug 5, 2004·Journal of Biomedical Materials Research. Part a·S LossdörferB D Boyan
Dec 29, 2004·Growth Factors·Di ChenGregory R Mundy
Aug 17, 2005·Journal of Periodontology·Effie Ioannidou, Aikaterini Doufexi
Aug 20, 2005·The Journal of Biological Chemistry·Fumitaka KugimiyaUng-il Chung
Nov 5, 2005·Journal of Biomedical Materials Research. Part a·F RuppJ Geis-Gerstorfer
Aug 22, 2006·Clinical Implant Dentistry and Related Research·Gabriel MonovReinhard Gruber
Feb 27, 2007·Journal of Biomedical Materials Research. Part a·Zhe QuAndreas Schedle
Mar 16, 2007·Journal of Clinical Periodontology·Nagihan BostanciGeorgios N Belibasakis
May 1, 2007·Dental Materials : Official Publication of the Academy of Dental Materials·Xiaohui Rausch-fanAndreas Schedle
Dec 18, 2007·Clinical Oral Implants Research·Fatih ArikanNecil Kütükçüler
Feb 23, 2008·Journal of Tissue Engineering and Regenerative Medicine·P C BessaR L Reis
Aug 12, 2009·Clinical Oral Implants Research·Ann Wennerberg, Tomas Albrektsson
Aug 12, 2009·Clinical Oral Implants Research·Rüdiger JunkerJohn A Jansen
Aug 28, 2009·Clinical Oral Implants Research·Heba AbuhusseinHom-Lay Wang
Nov 13, 2010·Clinical Oral Implants Research·Anastasios A MamalisMichael Koutsilirieris
May 13, 2011·Clinical Oral Implants Research·Niklaus P LangDieter D Bosshardt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Oral Implants Research
Fatih ArikanNecil Kütükçüler
American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics
Sukru EnhosTancan Uysal
© 2022 Meta ULC. All rights reserved