Monitoring Central Venous Catheter Resistance to Predict Imminent Occlusion: A Prospective Pilot Study

PloS One
Joshua WolfPatricia M Flynn

Abstract

Long-term central venous catheters are essential for the management of chronic medical conditions, including childhood cancer. Catheter occlusion is associated with an increased risk of subsequent complications, including bloodstream infection, venous thrombosis, and catheter fracture. Therefore, predicting and pre-emptively treating occlusions should prevent complications, but no method for predicting such occlusions has been developed. We conducted a prospective trial to determine the feasibility, acceptability, and efficacy of catheter-resistance monitoring, a novel approach to predicting central venous catheter occlusion in pediatric patients. Participants who had tunneled catheters and were receiving treatment for cancer or undergoing hematopoietic stem cell transplantation underwent weekly catheter-resistance monitoring for up to 12 weeks. Resistance was assessed by measuring the inline pressure at multiple flow-rates via a syringe pump system fitted with a pressure-sensing transducer. When turbulent flow through the device was evident, resistance was not estimated, and the result was noted as "non-laminar." Ten patients attended 113 catheter-resistance monitoring visits. Elevated catheter resistance (>8.8% increase) was ...Continue Reading

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Citations

Jan 9, 2016·JPEN. Journal of Parenteral and Enteral Nutrition·Melissa A ShenepJoshua Wolf
Oct 30, 2016·British Journal of Nursing : BJN·Scott M Gouveia
Dec 28, 2018·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Christina Boord
Sep 3, 2016·PloS One·Paula Parás-BravoFrancisco Manuel Antolín-Juárez
Oct 25, 2020·Worldviews on Evidence-based Nursing·Eugene SlaughterSamantha J Keogh
Aug 26, 2019·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·Hongxiu ChenXiuying Hu

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Clinical Trials Mentioned

NCT01737554

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