Monitoring change in spatial patterns of disease: comparing univariate and multivariate cumulative sum approaches

Statistics in Medicine
P A Rogerson, Ikuho Yamada

Abstract

Prospective disease surveillance has gained increasing attention, particularly in light of recent concern for quick detection of bioterrorist events. Monitoring of health events has the potential for the detection of such events, but the benefits of surveillance extend much more broadly to the quick detection of change in public health. In this paper, univariate and multivariate cumulative sum methods for disease surveillance are compared. Although the univariate method has been previously used in the context of health surveillance, the multivariate method has not. The univariate approach consists of simultaneously and independently monitoring the disease rate in each region; the multivariate approach accounts explicitly for any covariation between regions. The univariate approaches are limited by their lack of ability to account for the spatial autocorrelation of regional data; the multivariate methods are limited by the difficulty in accurately specifying the multiregional covariance structure. The methods are illustrated using both simulated data and county-level data on breast cancer in the northeastern United States. When the degree of spatial autocorrelation is low, the univariate method is generally better at detecting c...Continue Reading

References

Jul 15, 1997·American Journal of Epidemiology·M KulldorffL S Freedman
Oct 6, 1997·Statistics in Medicine·P A Rogerson
Jan 5, 2002·Biometrics·M J Daniels, R E Kass

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Citations

Apr 27, 2012·Statistical Methods in Medical Research·A Corberán-Vallet
Apr 12, 2008·International Journal of Health Geographics·Kunihiko TakahashiKatherine Yih
Mar 17, 2010·International Journal of Health Geographics·Colin Robertson, Trisalyn A Nelson
Jul 1, 2010·Spatial and Spatio-temporal Epidemiology·Colin RobertsonAndrew B Lawson
Aug 24, 2006·Statistics in Medicine·J Brooke MarshallWilliam H Woodall
Mar 6, 2012·Statistics in Medicine·Matthew J HeatonFrancisco Vera
Feb 12, 2011·Statistics in Medicine·Wei JiangWilliam H Woodall
Feb 12, 2011·Statistics in Medicine·Ronald D Fricker
Apr 3, 2015·Biometrics·Jingnan ZhangPeihua Qiu
May 31, 2015·Proceedings of the National Academy of Sciences of the United States of America·Zhou FanDavid E Shaw
Jun 23, 2009·Preventive Veterinary Medicine·Michael HöhleLeonhard Held
Feb 28, 2020·Statistics in Medicine·An-Ting JhuangBrian J Reich
Nov 27, 2019·Scientific Reports·Liu LiuJian Zhang

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