Monitoring cornea and graft morphometric dynamics after descemet stripping and endothelial keratoplasty with anterior segment optical coherence tomography

Cornea
Dorota Tarnawska, Edward Wylegala

Abstract

To evaluate the dynamics of cornea and graft thickness after Descemet stripping and endothelial keratoplasty (DSEK) using anterior segment optical coherence tomography (AS-OCT) and to assess the usefulness of AS-OCT in monitoring graft adherence after DSEK. Eighty-eight eyes from 86 patients underwent DSEK for Fuchs endothelial dystrophy or pseudophakic bullous keratopathy. Central corneal thickness (CCT), endothelial graft thickness (GT), interface fluid presence, graft dislocation, rate of CCT, and GT changes were measured with an AS-OCT during 12-month follow up. The CCT averaged 788 microm preoperatively. On postoperative Day 1, mean CCT was 816 microm and GT was 191 microm. Compared with CCT on the first day, the changes in CCT on 2, 3, and 7 days were statistically nonsignificant. From 1 month to 12 months after DSEK, the CCT significantly diminished (P < 0.001). The CCT dynamics closely correlated with changes of GT and of the recipient's part of cornea. The most rapid rate of thickness decrease was observed between 1 week and 1 month: 5.34 microm/day for the entire cornea and 2.54 microm/day for endothelial disc. Between 1 month and 1 year, the CCT and GT were stable with only a trend toward further decrease. Entrapped ...Continue Reading

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Citations

Mar 24, 2012·Journal of Cataract and Refractive Surgery·Maninder S Bhogal, Bruce D Allan
Jul 9, 2010·Journal of Cataract and Refractive Surgery·Muriël DoorsRudy M M A Nuijts
Dec 14, 2011·American Journal of Ophthalmology·Sunita ChaurasiaMuralidhar Ramappa
Nov 21, 2012·Seminars in Ophthalmology·Rony R Sayegh, Roberto Pineda
Jul 30, 2014·International Ophthalmology·Jan D UnterlauftGerd Geerling
Feb 5, 2013·Acta Biomaterialia·Berkay OzcelikGreg G Qiao
Jul 23, 2020·European Journal of Ophthalmology·Pedro BertinoLuciene Barbosa de Sousa
Sep 29, 2019·Investigative Ophthalmology & Visual Science·Munetoyo TodaJunji Hamuro
May 22, 2020·Progress in Retinal and Eye Research·Stephan Ong ToneUla V Jurkunas

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