Monitoring corneal densities following primary pterygium excision with adjuvant topical mitomycin-C application--an observational study of corneal scar changes

Cornea
Ka Wai KamAlvin L Young

Abstract

Corneal densitometry is an inherent feature of the Pentacam device. We aim to assess the changes in corneal scar density with serial Scheimpflug images following primary pterygium excision with topical application of mitomycin-C. We recruited patients who underwent primary, single-headed pterygium excision with topical adjuvant mitomycin-C. Scheimpflug images were taken at postoperative weeks 1, 4, and 12, and all patients received topical corticosteroid and antibiotic treatment for at least 4 weeks postoperatively. Corneal scar densities were generated by the software for analysis. Secondary outcome measures included intraocular pressures and pterygium recurrence at the end of 12 weeks. Changes in corneal densities between weeks 12, 4, and 1 were calculated. We recruited 31 eyes of 31 patients, of whom 16 were male patients and 15 were female patients, with 19 left and 12 right eyes. Mean age at operation was 62.0 ± 9.4 years. Mean reduction in density of the anterior 120 μm of cornea was -3.07 [95% confidence interval (CI), -6.600 to 0.460] and -3.455 (95% CI, -6.787 to -0.122) at postoperative 4 and 12 weeks, respectively, and mean reduction percentage was -4.7% (95% CI, -10.7% to 1.3%) and -6.3% (95% CI, -11.8% to -0.7%), r...Continue Reading

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Citations

Oct 25, 2016·Ophthalmology·Maged AlnawaisehGerold Mönnig
May 18, 2017·Indian Journal of Ophthalmology·Rohit ShettyChaitra Jayadev
Feb 23, 2018·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M Alnawaiseh, N Eter
Mar 8, 2019·Cutaneous and Ocular Toxicology·Emine SenUfuk Elgin
Jun 21, 2018·International Ophthalmology·Ka Wai KamAlvin L Young
Apr 17, 2021·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Marta Jiménez-GarcíaJos J Rozema
Jun 15, 2021·Frontiers in Pharmacology·Vishal JhanjiGary Hin-Fai Yam

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