Monitoring of adenovirus from conjunctival scrapings in Japan during 2005--2006

Journal of Medical Virology
Kiyohiko MatsuiKenji Okuda

Abstract

A total of 189 conjunctival scrapings were collected from patients in Tokyo, Japan by monitoring adenovirus infection in community-based clinics during 2005 and 2006. Of the 189 samples, 155 (82%) had adenoviruses detected by polymerase chain reaction (PCR). The serotypes were determined by PCR-restriction fragment length polymorphism (PCR-RFLP) analysis, using a combination of endonucleases, such as HhaI, AluI, and HaeIII, and neutralization tests (NTs). PCR-RFLP identified five serotypes: serotype 3: 16.8%, serotype 4: 9.7%, serotype 8: 34.8%, serotype 11: 23.2%, and serotype 37: 15.5%. Adenovirus 8 was the most common serotype identified. A subset consisting of 25 isolates identified as adenovirus 8 from this study plus 25 isolates from Kawasaki were analyzed using PCR sequencing of the hexon gene. Compared with prototype adenovirus serotype 8 and serotype 9 derived in Tokyo and Kawasaki, these isolates shared 61.7-62.8% and 80.5-82.7% amino acid homology, respectively, suggesting that a variant adenovirus serotype 8 was involved in this outbreak, and is different from the prototype adenovirus 8 virus. This variant had not been detected in Japan prior to 1996 and appears to be the most common adenovirus type 8 involved in ca...Continue Reading

References

Jun 1, 1992·The Journal of General Virology·C I ToogoodR T Hay
Dec 1, 1989·The Journal of Infectious Diseases·D WarrenL J Anderson
Jan 1, 1994·Research in Virology·P Pring-Akerblom, T Adrian
Sep 1, 1996·Journal of Clinical Microbiology·W Saitoh-InagawaH Ishiko
May 1, 1997·Research in Virology·P Pring-AkerblomT Köstler
May 15, 1999·Journal of Clinical Microbiology·S TakeuchiS Ohno
Oct 3, 1999·Journal of Virological Methods·S K Poddar
Jun 2, 2000·Journal of Clinical Microbiology·E M ElnifroA S Bailey
Feb 1, 2003·Journal of Clinical Pathology·A K AdhikaryN Okabe
Feb 10, 2004·Journal of Clinical Microbiology·Arun Kumar AdhikaryNobuhiko Okabe
Jan 19, 2007·Journal of Clinical Microbiology·Rika Miura-OchiaiHiroaki Ishiko

❮ Previous
Next ❯

Citations

Jan 14, 2010·Archives of Virology·Leonardo FerreyraSilvia Nates
Jun 26, 2009·Current Medical Research and Opinion·Terrence P O'BrienMichael B Raizman
Oct 19, 2010·Enfermedades infecciosas y microbiología clínica·Juncal ArtiedaJosune Mendiola
Oct 27, 2009·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Mark G LebeckGregory C Gray
Sep 10, 2014·Journal of Medical Virology·Begüm Nalça ErdinA Arzu Sayıner
Mar 22, 2018·BMC Infectious Diseases·Jie LiQuanyi Wang
Aug 2, 2019·Japanese Journal of Infectious Diseases·Hisatoshi KanekoTsuguto Fujimoto
Mar 12, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kristen K ColemanGregory C Gray

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Gregory C GrayDean D Erdman
Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Troy McCarthyGregory C Gray
© 2022 Meta ULC. All rights reserved