PMID: 9537661Apr 16, 1998Paper

Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intraarterial thrombolysis: case report

Surgical Neurology
H NagashimaT Iwashita

Abstract

The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thrombolytic therapy for middle cerebral artery (MCA) occlusion is discussed. To obtain real-time data on changing cerebral hemodynamics, near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediately after intraarterial injection of urokinase (UK). A steady increase in regional oxygen saturation (rSO2) was observed until recanalization was confirmed angiographically as a result of 300,000 IU of UK. Monitoring of cerebrovascular hemoglobin saturation by NIRS is a simple, noninvasive technique suggesting its potential for intraoperative monitoring during interventional neuroradiologic procedures.

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Citations

Jul 17, 1999·Progress in Neurobiology·P L Madsen, N H Secher
Jun 5, 2002·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·Péter BönöczkZoltán Nagy
Oct 1, 2015·PloS One·Sou NobukawaJian-Qin Liu
Apr 11, 2000·Neurologic Clinics·K Becker
Mar 16, 2018·Biomedical Optics Express·Raquel Delgado-MederosJoan Martí-Fàbregas
Jun 15, 2000·Anaesthesia and Intensive Care·P L Madsen, N H Secher

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