Monitoring of flaps by measurement of intracapillary haemoglobin oxygenation with EMPHO II: experimental and clinical study

The British Journal of Oral & Maxillofacial Surgery
K D WolffK H Frank

Abstract

To find out whether measurements of intracapillary haemoglobin oxygenation made with the non-invasive Erlangen microlightguide spectrophotometer (EMPHO II) provided accurate data about the oxygen supply as well as the blood flow to free flaps in rats and humans. Experimental, and prospective open clinical study. University hospital, Germany. ANIMALS and Thirty male Wistar rats and 20 patients who underwent microsurgical transplant of free flaps (radial forearm, n = 8; osteocutaneous fibula, n = 7; and myocutaneous from the lateral thigh, n = 5). Measurement of the haemoglobin oxygenation of the skin before, during, and after transfer of the flap. Reproducibility and mean curves for haemoglobin oxygenation and haemoglobin concentration. All values were reproducible, and there were only slight fluctuations. Uninjured skin in rats (baseline value) oxygenation of the total haemoglobin concentration ranged from 15% to 45% (mean 23%). After the flaps were raised there was a slight increase (to a mean of 37%), probably as a result of reactive hyperaemia. There was a rapid decrease within a few minutes of arterial occlusion, and residual oxygenation of up to 20% after perfusion stopped. The flap was totally deoxygenated after 1 h. Veno...Continue Reading

References

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Citations

Mar 27, 2012·Operative Orthopädie und Traumatologie·K KnoblochP M Vogt
Oct 17, 1998·Plastic and Reconstructive Surgery·K D WolffU Mansmann
Jun 21, 2012·Journal of Cancer Research and Clinical Oncology·Bettina Hohlweg-MajertSteffi Pigorsch
Sep 6, 2005·Oral Oncology·B SwinsonC Hopper
Dec 14, 2005·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Frank HölzleKlaus-Dietrich Wolff
May 29, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Andrej RepezZoran M Arnez
Aug 28, 2003·Microsurgery·Frank HölzleKlaus-Dietrich Wolff
Jul 12, 2003·Pain·M KobanF Birklein
Apr 7, 2021·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Martin MolitorStefano Lucchina
Apr 24, 2010·International Journal of Oral and Maxillofacial Surgery·S T BeckerH Terheyden

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