Monitoring olfactory function in chronic rhinosinusitis and the effect of disease duration on outcome

International Forum of Allergy & Rhinology
Katherine L WhitcroftThomas Hummel

Abstract

Our primary aim in this study was to determine which of the "Sniffin' Sticks" subtest components (threshold, discrimination, or identification) best reflect overall change in olfactory function during treatment for chronic rhinosinusitis (CRS). Our secondary aim was to determine whether duration of CRS affects olfactory outcomes after treatment. A retrospective cohort study was performed. Sniffin' Sticks test scores from patients medically treated for CRS at our center from 1999 to 2016 were analyzed. Only patients with 2 test scores available were included. Results from 408 patients were included (mean age, 56 years; male:female ratio, 217:191). There was a statistically significant improvement in threshold (T), discrimination (D), and identification (I) scores as well as the composite "TDI" score between the two testing sessions. Controlling for age, there was a significantly greater improvement in composite TDI score in patients with CRS of ≤24 months duration. As expected, we found statistically significant correlations between change in overall composite TDI score and change in threshhold, discrimination, and identification, between sessions. Of the individual subcomponents, change in discrimination correlated best with ch...Continue Reading

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Citations

Feb 14, 2020·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Gwanghui RyuDae Woo Kim
Jun 18, 2019·Endocrine, Metabolic & Immune Disorders Drug Targets·Burak YulugErtugrul Kilic
Jul 22, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Dawei WuYongxiang Wei
Jul 8, 2018·International Forum of Allergy & Rhinology·Sarah K Wise
Sep 10, 2020·Laryngoscope Investigative Otolaryngology·Chia-Hung LiPeter Andrews
Dec 29, 2020·Laryngoscope Investigative Otolaryngology·Xiaoguang YanThomas Hummel
Feb 19, 2021·OTO Open : the Official Open Access Journal of the American Academy of Otolaryngology--Head and Neck Surgery Foundation·James H KimElisabeth H Ference

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