Monitoring plasma antibiotic concentrations in Spanish hospitals

Enfermedades infecciosas y microbiología clínica
Francisco Alvarez-LermaGEIPC-SEIMC

Abstract

Monitoring of plasma aminoglycoside and vancomycin concentrations is a measure of good clinical practice in critically ill patients. However, the frequency and application of this practice in Spanish hospitals is unknown. Observational, multicenter study based on a survey designed by the Study Group for Infection in the Critically Ill Patient of the Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC, Spanish Society of Infectious Diseases and Clinical Microbiology). The survey was sent to the 221 general hospitals with a more than 150-bed capacity included in the hospital directory. Questions regarding the antibiotics monitored, hospital services involved, systems used to report the results, and levels of intervention were included. Information was recorded from 56 (25.3%) hospitals with a total of 36,886 beds, among which 933 (2.5%) corresponded to critically ill patients. In 47 (83.9%) hospitals, plasma concentrations of one or two antibiotics were determined: vancomycin in 47 (83.9% of the total), amikacin in 41 (73.2%), and gentamicin in 40 (71.2%). Analyses were performed by the following services: Biochemistry in 34%, Pharmacy in 25.5% and Pharmacology in 8.5%. Only 57.4% of services recommended ...Continue Reading

Citations

Sep 12, 2008·Farmacia hospitalaria : órgano oficial de expresión científica de la Sociedad Española de Farmacia Hospitalaria·UNKNOWN Grupo de Estudio de Infección en el paciente crítico (GEIPC-SEIMC)Daniel Fatela
Apr 3, 2008·Enfermedades infecciosas y microbiología clínica·Francisco Alvarez-LermaUNKNOWN Grupo de Estudio de Infección en el paciente crítico (GEIPC-SEIMC)

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