Monitoring the pressure of the sphincter of Oddi by percutaneous transhepatic choledochoscopy: new method for evaluating motor function

Gastroenterologia Japonica
J KanohY Tsukamoto


The pressure of the sphincter of Oddi was measured in 40 patients using a thin microtransducer introduced via percutaneous transhepatic choledochoscopy. Choledochograms of the Vaterian bile duct were classified into four types: N (normal), I, II and III. Judging from the length of the Vaterian bile duct and the degree of fibrosis observed in the biopsy specimens, duodenal papillitis was found to be more severe in Type III than in Type II. Nevertheless the systolic pressure was significantly lower in Type III. We considered that when duodenal papillitis is considerably advanced, the force of contraction of the sphincter is reduced. In addition, based on choledochoscopic observations, as duodenal papillitis increased in severity, the incidence of an irregular shape at the end of the common bile duct during diastole increased. The indications for endoscopic sphincterotomy were determined based on the pressure of the sphincter of Oddi in patients with normal duodenal papilla. In the 26 patients in whom the procedure was not indicated, no gallstones developed. In the 3 patients in whom the procedure was indicated and performed, gallstones have not developed. However, 3 of the 6 patients in whom the procedure was indicated but not pe...Continue Reading


Jun 1, 1979·Digestive Diseases and Sciences·J A LoGiudiceW J Dodds
Aug 31, 1978·Gastrointestinal Radiology·D S ZimmonA R Clemett
Feb 1, 1975·Gastrointestinal Endoscopy·O T Nebel
Mar 1, 1987·Scandinavian Journal of Gastroenterology·P Funch-JensenJ Ravnsbaek

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.